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Items: 6

1.

Herpes simplex

A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.) [from MeSH]

MedGen UID:
9234
Concept ID:
C0019348
Disease or Syndrome
2.

Herpes

Any inflammatory skin disease caused by a herpesvirus and characterized by the formation of small vesicles in clusters. [from NCI]

MedGen UID:
6821
Concept ID:
C0019340
Disease or Syndrome
3.

Pheochromocytoma

Hereditary paraganglioma-pheochromocytoma (PGL/PCC) syndromes are characterized by paragangliomas (tumors that arise from neuroendocrine tissues symmetrically distributed along the paravertebral axis from the base of the skull to the pelvis) and by pheochromocytomas (paragangliomas that are confined to the adrenal medulla). Sympathetic paragangliomas hypersecrete catecholamines; parasympathetic paragangliomas are most often nonsecretory. Extra-adrenal parasympathetic paragangliomas are located predominantly in the skull base, neck, and upper medistinum; approximately 95% of such tumors are nonsecretory. In contrast, sympathetic extra-adrenal paragangliomas are generally confined to the lower mediastinum, abdomen, and pelvis, and are typically secretory. Pheochromocytomas, which arise from the adrenal medulla, typically hypersecrete catecholamines. Symptoms of PGL/PCC result either from mass effects or catecholamine hypersecretion (e.g., sustained or paroxysmal elevations in blood pressure, headache, episodic profuse sweating, forceful palpitations, pallor, and apprehension or anxiety). The risk for malignant transformation is greater for extra-adrenal sympathetic paragangliomas than for pheochromocytomas or skull base and neck paragangliomas. [from GTR]

MedGen UID:
18419
Concept ID:
C0031511
Neoplastic Process
4.

Pheochromocytoma

Pheochromocytomas (also known as chromaffin tumors) produce, store, and secrete catecholamines. Pheochromocytomas usually originate from the adrenal medulla but may also develop from chromaffin cells in or about sympathetic ganglia. A common symptom of pheochromocytoma is hypertension owing to release of catecholamines. [from HPO]

MedGen UID:
505323
Concept ID:
CN002423
Finding
5.

Viral Vector

A viral gene transduction agent used to transfer genes or genetic materials, such as retroviruses and adenoviruses. [from NCI]

MedGen UID:
274399
Concept ID:
C1520007
Pharmacologic Substance
6.

Rat Adrenal Gland Pheochromocytoma

A benign or malignant neuroendocrine neoplasm of the rat sympathetic nervous system that secretes catecholamines. It arises from the chromaffin cells of the rat adrenal medulla. [from NCI]

MedGen UID:
887450
Concept ID:
C4054122
Neoplastic Process
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