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Insulin

MedGen UID:
5827
Concept ID:
C0021641
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
Synonyms: Insulin, Regular; Insulin, Soluble; Regular Insulin; Soluble Insulin
SNOMED CT: Insulin (67866001); Regular insulin product (39487003); Unmodified insulin product (39487003); Regular insulin (412222002); Insulin product (39487003); Insulin preparation (39487003)
 

Definition

Insulin (51 aa, ~6 kDa) is encoded by the human INS gene. This protein is involved in the direct regulation of glucose metabolism. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInsulin

Recent clinical studies

Etiology

Chamarthi B, Cincotta AH
Postgrad Med 2017 May;129(4):446-455. Epub 2017 Apr 12 doi: 10.1080/00325481.2017.1315290. PMID: 28374645
Seyedi F, Farsinejad A, Nematollahi-Mahani SN
Tissue Cell 2017 Apr;49(2 Pt B):227-232. Epub 2017 Mar 8 doi: 10.1016/j.tice.2017.03.001. PMID: 28343707
Wysham CH, Lin J, Kuritzky L
Postgrad Med 2017 May;129(4):436-445. Epub 2017 Mar 15 doi: 10.1080/00325481.2017.1297669. PMID: 28294702
Natali A, Baldi S, Bonnet F, Petrie J, Trifirò S, Tricò D, Mari A; RISC Investigators.
Metabolism 2017 Apr;69:33-42. Epub 2017 Jan 6 doi: 10.1016/j.metabol.2017.01.001. PMID: 28285650
Larsen PB, Linneberg A, Hansen T, Friis-Hansen L
Clin Biochem 2017 May;50(7-8):408-413. Epub 2016 Dec 16 doi: 10.1016/j.clinbiochem.2016.12.004. PMID: 27989491

Diagnosis

Seyedi F, Farsinejad A, Nematollahi-Mahani SN
Tissue Cell 2017 Apr;49(2 Pt B):227-232. Epub 2017 Mar 8 doi: 10.1016/j.tice.2017.03.001. PMID: 28343707
Natali A, Baldi S, Bonnet F, Petrie J, Trifirò S, Tricò D, Mari A; RISC Investigators.
Metabolism 2017 Apr;69:33-42. Epub 2017 Jan 6 doi: 10.1016/j.metabol.2017.01.001. PMID: 28285650
Karimian Azari E, Smith KR, Yi F, Osborne TF, Bizzotto R, Mari A, Pratley RE, Kyriazis GA
Am J Clin Nutr 2017 Apr;105(4):1001-1009. Epub 2017 Mar 1 doi: 10.3945/ajcn.116.146001. PMID: 28251932Free PMC Article
Chhasatia R, Sweetman MJ, Harding FJ, Waibel M, Kay T, Thomas H, Loudovaris T, Voelcker NH
Biosens Bioelectron 2017 May 15;91:515-522. Epub 2017 Jan 4 doi: 10.1016/j.bios.2017.01.004. PMID: 28082240
Xuan NT, Hoang NH, Nhung VP, Duong NT, Ha NH, Hai NV
J Recept Signal Transduct Res 2017 Jun;37(3):297-303. Epub 2016 Nov 3 doi: 10.1080/10799893.2016.1247862. PMID: 27808000

Therapy

Chamarthi B, Cincotta AH
Postgrad Med 2017 May;129(4):446-455. Epub 2017 Apr 12 doi: 10.1080/00325481.2017.1315290. PMID: 28374645
Bailey TS, Stone JY
Expert Opin Drug Deliv 2017 May;14(5):697-703. Epub 2017 Apr 10 doi: 10.1080/17425247.2017.1313831. PMID: 28359171
P V J, Nair SV, Kamalasanan K
Colloids Surf B Biointerfaces 2017 May 1;153:123-131. Epub 2017 Feb 17 doi: 10.1016/j.colsurfb.2017.02.017. PMID: 28235722
Larsen PB, Linneberg A, Hansen T, Friis-Hansen L
Clin Biochem 2017 May;50(7-8):408-413. Epub 2016 Dec 16 doi: 10.1016/j.clinbiochem.2016.12.004. PMID: 27989491
Xuan NT, Hoang NH, Nhung VP, Duong NT, Ha NH, Hai NV
J Recept Signal Transduct Res 2017 Jun;37(3):297-303. Epub 2016 Nov 3 doi: 10.1080/10799893.2016.1247862. PMID: 27808000

Prognosis

Willis M, Asseburg C, Nilsson A, Johnsson K, Kartman B
Value Health 2017 Mar;20(3):357-371. Epub 2016 Dec 1 doi: 10.1016/j.jval.2016.10.004. PMID: 28292480
Park SK, Oh CM, Jung T, Choi YJ, Chung JY, Ryoo JH
Maturitas 2017 Apr;98:1-6. Epub 2017 Jan 12 doi: 10.1016/j.maturitas.2017.01.001. PMID: 28274322
Larsen PB, Linneberg A, Hansen T, Friis-Hansen L
Clin Biochem 2017 May;50(7-8):408-413. Epub 2016 Dec 16 doi: 10.1016/j.clinbiochem.2016.12.004. PMID: 27989491
Steiner E, Kazianka L, Breuer R, Hacker M, Wadsak W, Mitterhauser M, Stimpfl T, Reiter B, Karanikas G, Miholic J
Eur J Nucl Med Mol Imaging 2017 Mar;44(3):509-516. Epub 2016 Jul 7 doi: 10.1007/s00259-016-3451-0. PMID: 27389029
Sit KC, van Lonkhuyzen D, Walsh T, Croll T
J Biomol Struct Dyn 2017 Mar;35(4):857-867. Epub 2016 May 20 doi: 10.1080/07391102.2016.1165631. PMID: 27137342

Clinical prediction guides

Palivec V, Viola CM, Kozak M, Ganderton TR, Křížková K, Turkenburg JP, Halušková P, Žáková L, Jiráček J, Jungwirth P, Brzozowski AM
J Biol Chem 2017 May 19;292(20):8342-8355. Epub 2017 Mar 27 doi: 10.1074/jbc.M117.775924. PMID: 28348075Free PMC Article
Seyedi F, Farsinejad A, Nematollahi-Mahani SN
Tissue Cell 2017 Apr;49(2 Pt B):227-232. Epub 2017 Mar 8 doi: 10.1016/j.tice.2017.03.001. PMID: 28343707
Natali A, Baldi S, Bonnet F, Petrie J, Trifirò S, Tricò D, Mari A; RISC Investigators.
Metabolism 2017 Apr;69:33-42. Epub 2017 Jan 6 doi: 10.1016/j.metabol.2017.01.001. PMID: 28285650
Park SK, Oh CM, Jung T, Choi YJ, Chung JY, Ryoo JH
Maturitas 2017 Apr;98:1-6. Epub 2017 Jan 12 doi: 10.1016/j.maturitas.2017.01.001. PMID: 28274322
Tohidi M, Arbab P, Ghasemi A
Scand J Clin Lab Invest 2017 Apr;77(2):122-129. Epub 2017 Feb 2 doi: 10.1080/00365513.2016.1278260. PMID: 28150502

Recent systematic reviews

Wysham CH, Lin J, Kuritzky L
Postgrad Med 2017 May;129(4):436-445. Epub 2017 Mar 15 doi: 10.1080/00325481.2017.1297669. PMID: 28294702
Oryan A, Alemzadeh E
Life Sci 2017 Apr 1;174:59-67. Epub 2017 Mar 2 doi: 10.1016/j.lfs.2017.02.015. PMID: 28263805
Liu Y, Li J, Wang T, Wang Y, Zhao L, Fang Y
Maturitas 2017 Mar;97:44-52. Epub 2016 Dec 28 doi: 10.1016/j.maturitas.2016.12.004. PMID: 28159061
Wang F, Han L, Hu D
Clin Chim Acta 2017 Jan;464:57-63. Epub 2016 Nov 9 doi: 10.1016/j.cca.2016.11.009. PMID: 27836689
Islam MA, Bhayye S, Adeniyi AA, Soliman ME, Pillay TS
J Biomol Struct Dyn 2017 Mar;35(4):724-737. Epub 2016 Apr 14 doi: 10.1080/07391102.2016.1160258. PMID: 26950281

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