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Items: 3

1.

Haloperidol

A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity. [from NCI]

MedGen UID:
42327
Concept ID:
C0018546
Organic Chemical; Pharmacologic Substance
2.

Torsades de pointes

A type of ventricular tachycardia characterized by polymorphioc QRS complexes that change in amplitue and cycle length, and thus have the appearance of oscillating around the baseline in the EKG. [from HPO]

MedGen UID:
21214
Concept ID:
C0040479
Disease or Syndrome
3.

Torsade de pointes

MedGen UID:
409592
Concept ID:
C1963250
Finding
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