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Items: 5

1.

Warfarin

A drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners). [from NCI_NCI-GLOSS]

MedGen UID:
22695
Concept ID:
C0043031
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
2.

Hemorrhage

Bleeding is the loss of blood. It can happen inside or outside the body. Bleeding can be a reaction to a cut or other wound. It can also result from an injury to internal organs. There are many situations in which you might bleed. A bruise is bleeding under the skin. Some strokes are caused by bleeding in the brain. Other bleeding, such as gastrointestinal bleeding, coughing up blood, or vaginal bleeding, can be a symptom of a disease. Normally, when you bleed, your blood forms clots to stop the bleeding. Severe bleeding may require first aid or a trip to the emergency room. If you have a bleeding disorder, your blood does not form clots normally.  [from MedlinePlus]

MedGen UID:
5503
Concept ID:
C0019080
Pathologic Function
3.

Anti-Infective Agents

A pharmacological agent that can kill or prevent the reproduction of infectious organisms. [from NCI]

MedGen UID:
324
Concept ID:
C0003204
Pharmacologic Substance
4.

Anti-Infective Agents, Urinary

Substances capable of killing agents causing urinary tract infections or of preventing them from spreading. [from MeSH]

MedGen UID:
1964
Concept ID:
C0003207
Pharmacologic Substance
5.

Warfarin sodium

The sodium salt form of warfarin, a coumarin and a vitamin K antagonist, with anticoagulant activity. Warfarin sodium inhibits both vitamin K and vitamin K epoxide reductases, thereby interfering with the cyclic interconversion of vitamin K epoxide to its reduced form, vitamin KH2. Vitamin KH2 is a cofactor for the carboxylation of glutamate residues on the N-terminal regions of vitamin K-dependent proteins. As a result, maturation of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is inhibited. Without these coagulation factors, thrombogenesis and blood clot formation are prevented. [from NCI]

MedGen UID:
87667
Concept ID:
C0376218
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
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