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Items: 6

1.

sitagliptin

An orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis. [from NCI]

MedGen UID:
290563
Concept ID:
C1565750
Organic Chemical; Pharmacologic Substance
2.

Insulin Glargine

A drug used to control the amount of sugar in the blood of patients with diabetes. It is a form of the hormone insulin that is made in the laboratory. Insulin glargine controls blood sugar longer than insulin does. It is a type of therapeutic insulin. [from NCI_NCI-GLOSS]

MedGen UID:
172793
Concept ID:
C0907402
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
3.

exenatide

A 39 amino acid peptide and synthetic version of exendin-4, a hormone found in the saliva of the venomous lizard Gila monster, with insulin secretagogue and antihyperglycemic activity. Exenatide is administered subcutaneously and mimics human glucagon-like peptide-1 (GLP-1). Compared to GLP-1, exenatide has a longer half-life of 2.4 hours. [from NCI]

MedGen UID:
104090
Concept ID:
C0167117
Amino Acid, Peptide, or Protein; Pharmacologic Substance
4.

Glucose

A type of sugar; the chief source of energy for living organisms. [from NCI_NCI-GLOSS]

MedGen UID:
42238
Concept ID:
C0017725
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
5.

Metformin

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289) [from MeSH]

MedGen UID:
7578
Concept ID:
C0025598
Organic Chemical; Pharmacologic Substance
6.

Insulin

Insulin (51 aa, ~6 kDa) is encoded by the human INS gene. This protein is involved in the direct regulation of glucose metabolism. [from NCI]

MedGen UID:
5827
Concept ID:
C0021641
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
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