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Propranolol

MedGen UID:
19504
Concept ID:
C0033497
Organic Chemical; Pharmacologic Substance
Synonyms: 2-Propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)-; Propanolol
Drug response:
Propranolol response
MedGen UID:
450474
Concept ID:
CN078002
Sign or Symptom
SNOMED CT: Propranolol (372772003); Propranolol (55745002)
 

Definition

A synthetic, nonselective beta-adrenergic receptor blocker with antianginal, antiarrhythmic, antihypertensive properties. Propranolol competitively antagonizes beta-adrenergic receptors, thereby causing negative chronotropic and inotropic effects leading to a reduction in cardiac output. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPropranolol

Recent clinical studies

Etiology

Moyakine AV, Spillekom-van Koulil S, van der Vleuten CJM
J Am Acad Dermatol 2017 Jul;77(1):105-108. Epub 2017 Feb 9 doi: 10.1016/j.jaad.2017.01.025. PMID: 28190620
Sanghvi KP, Kabra NS, Padhi P, Singh U, Dash SK, Avasthi BS
Arch Dis Child Fetal Neonatal Ed 2017 Sep;102(5):F389-F394. Epub 2017 Jan 13 doi: 10.1136/archdischild-2016-311548. PMID: 28087723
Gupta V, Rawat R, Shalimar, Saraya A
Hepatol Int 2017 Mar;11(2):181-187. Epub 2016 Sep 13 doi: 10.1007/s12072-016-9765-y. PMID: 27624505
LeCompte MT, Rae L, Kahn SA
Burns 2017 Feb;43(1):121-126. Epub 2016 Aug 27 doi: 10.1016/j.burns.2016.07.007. PMID: 27575676
Ren W, Li S, Gao L, Huang S, Zhang L, Qiang C, Liu C, Zhi K
Pediatr Int 2017 Feb;59(2):213-217. Epub 2016 Nov 20 doi: 10.1111/ped.13109. PMID: 27473874

Diagnosis

Kim KH, Choi TH, Choi Y, Park YW, Hong KY, Kim DY, Choe YS, Lee H, Cheon JE, Park JB, Park KD, Kang HJ, Shin HY, Jeong JH
JAMA Dermatol 2017 Jun 1;153(6):529-536. doi: 10.1001/jamadermatol.2017.0250. PMID: 28423174
Bolin EH, Lang SM, Tang X, Collins RT
Am J Cardiol 2017 May 15;119(10):1605-1610. Epub 2017 Mar 1 doi: 10.1016/j.amjcard.2017.02.017. PMID: 28363353
Santosh PJ, Bell L, Lievesley K, Singh J, Fiori F
BMC Pediatr 2016 Nov 29;16(1):194. doi: 10.1186/s12887-016-0734-3. PMID: 27899087Free PMC Article
Ösken A, Yelgeç NS, Zehir R, Öz TK, Yaylacı S, Akdemir R, Gündüz H
Indian J Pharmacol 2016 Jul-Aug;48(4):462-465. doi: 10.4103/0253-7613.186193. PMID: 27756965Free PMC Article
Hardison S, Wan W, Dodson KM
Int J Pediatr Otorhinolaryngol 2016 Nov;90:175-180. Epub 2016 Sep 13 doi: 10.1016/j.ijporl.2016.09.012. PMID: 27729127

Therapy

Schwartz T, Faria J, Pawar S, Siegel D, Chun RH
Laryngoscope 2017 Nov;127(11):2665-2672. Epub 2017 Aug 23 doi: 10.1002/lary.26818. PMID: 28833230
Moyakine AV, Spillekom-van Koulil S, van der Vleuten CJM
J Am Acad Dermatol 2017 Jul;77(1):105-108. Epub 2017 Feb 9 doi: 10.1016/j.jaad.2017.01.025. PMID: 28190620
Sanghvi KP, Kabra NS, Padhi P, Singh U, Dash SK, Avasthi BS
Arch Dis Child Fetal Neonatal Ed 2017 Sep;102(5):F389-F394. Epub 2017 Jan 13 doi: 10.1136/archdischild-2016-311548. PMID: 28087723
Gupta V, Rawat R, Shalimar, Saraya A
Hepatol Int 2017 Mar;11(2):181-187. Epub 2016 Sep 13 doi: 10.1007/s12072-016-9765-y. PMID: 27624505
LeCompte MT, Rae L, Kahn SA
Burns 2017 Feb;43(1):121-126. Epub 2016 Aug 27 doi: 10.1016/j.burns.2016.07.007. PMID: 27575676

Prognosis

Bolin EH, Lang SM, Tang X, Collins RT
Am J Cardiol 2017 May 15;119(10):1605-1610. Epub 2017 Mar 1 doi: 10.1016/j.amjcard.2017.02.017. PMID: 28363353
Ren W, Li S, Gao L, Huang S, Zhang L, Qiang C, Liu C, Zhi K
Pediatr Int 2017 Feb;59(2):213-217. Epub 2016 Nov 20 doi: 10.1111/ped.13109. PMID: 27473874
Hardison S, Wan W, Dodson KM
Int J Pediatr Otorhinolaryngol 2016 Nov;90:175-180. Epub 2016 Sep 13 doi: 10.1016/j.ijporl.2016.09.012. PMID: 27729127
Zamzow RM, Ferguson BJ, Stichter JP, Porges EC, Ragsdale AS, Lewis ML, Beversdorf DQ
Psychopharmacology (Berl) 2016 Apr;233(7):1171-8. Epub 2016 Jan 14 doi: 10.1007/s00213-015-4199-0. PMID: 26762378
Zhang F, Duan X, Zhang M, Li Z, He Q, Wang Y, Miao C, Zhong W, Zou X, Zhuge Y
J Gastroenterol Hepatol 2016 Apr;31(4):829-34. doi: 10.1111/jgh.13198. PMID: 26489037

Clinical prediction guides

Schwartz T, Faria J, Pawar S, Siegel D, Chun RH
Laryngoscope 2017 Nov;127(11):2665-2672. Epub 2017 Aug 23 doi: 10.1002/lary.26818. PMID: 28833230
Moyakine AV, Spillekom-van Koulil S, van der Vleuten CJM
J Am Acad Dermatol 2017 Jul;77(1):105-108. Epub 2017 Feb 9 doi: 10.1016/j.jaad.2017.01.025. PMID: 28190620
Ren W, Li S, Gao L, Huang S, Zhang L, Qiang C, Liu C, Zhi K
Pediatr Int 2017 Feb;59(2):213-217. Epub 2016 Nov 20 doi: 10.1111/ped.13109. PMID: 27473874
Hardison S, Wan W, Dodson KM
Int J Pediatr Otorhinolaryngol 2016 Nov;90:175-180. Epub 2016 Sep 13 doi: 10.1016/j.ijporl.2016.09.012. PMID: 27729127
Turhan AB, Bör Ö, Özdemir ZC
J Cosmet Dermatol 2016 Sep;15(3):296-302. Epub 2016 Apr 7 doi: 10.1111/jocd.12220. PMID: 27061310

Recent systematic reviews

Schwartz T, Faria J, Pawar S, Siegel D, Chun RH
Laryngoscope 2017 Nov;127(11):2665-2672. Epub 2017 Aug 23 doi: 10.1002/lary.26818. PMID: 28833230
Linde K, Rossnagel K
Cochrane Database Syst Rev 2017 Feb 17;2:CD003225. doi: 10.1002/14651858.CD003225.pub3. PMID: 28212466
Cardwell CR, Pottegård A, Vaes E, Garmo H, Murray LJ, Brown C, Vissers PA, O'Rorke M, Visvanathan K, Cronin-Fenton D, De Schutter H, Lambe M, Powe DG, van Herk-Sukel MP, Gavin A, Friis S, Sharp L, Bennett K
Breast Cancer Res 2016 Dec 1;18(1):119. doi: 10.1186/s13058-016-0782-5. PMID: 27906047Free PMC Article
Hardison S, Wan W, Dodson KM
Int J Pediatr Otorhinolaryngol 2016 Nov;90:175-180. Epub 2016 Sep 13 doi: 10.1016/j.ijporl.2016.09.012. PMID: 27729127
Steenen SA, van Wijk AJ, van der Heijden GJ, van Westrhenen R, de Lange J, de Jongh A
J Psychopharmacol 2016 Feb;30(2):128-39. Epub 2015 Oct 20 doi: 10.1177/0269881115612236. PMID: 26487439Free PMC Article

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