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Items: 14

1.

Osmotic diuretic

Compounds that increase urine volume by increasing the amount of osmotically active solute in the urine. Osmotic diuretics also increase the osmolarity of plasma. [from MeSH]

MedGen UID:
8452
Concept ID:
C0012800
Pharmacologic Substance
2.

Calcium

A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. [from MeSH]

MedGen UID:
710
Concept ID:
C0006675
Biologically Active Substance; Element, Ion, or Isotope; Pharmacologic Substance
3.

Stress

The negative mental, emotional, and physical reactions that occur when environmental stressors are perceived as exceeding the individual's adaptive capacities. [from NCI]

MedGen UID:
20971
Concept ID:
C0038435
Finding
4.

Calcium Binding

Calcium Binding consists of a biophysical interaction between one or more calcium ion(s) and a biological molecule, such as a protein. Calcium binding with proteins often involves interaction of the ion(s) with a specific region, domain, or motif (e.g., EF-Hand) that supports protein structure or induces an alteration of protein activity in enzymatic or cell signaling cascades. [from NCI]

MedGen UID:
271964
Concept ID:
C1516144
Molecular Function
5.

Positive

Involving advantage or good. [from NCI]

MedGen UID:
254858
Concept ID:
C1446409
Finding
6.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
7.

Osmitrol

MedGen UID:
152058
Concept ID:
C0699451
Organic Chemical; Pharmacologic Substance
8.

Osmofundin

MedGen UID:
148505
Concept ID:
C0699453
Organic Chemical; Pharmacologic Substance
9.

Physiological stress

The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions. [from MeSH]

MedGen UID:
105278
Concept ID:
C0449430
Pathologic Function
10.

Intracellular Second Messenger

A non-proteinaceous signaling molecule that is generated by intracellular enzymes that respond to the binding of extracellular ligands to cell surface receptors. These compounds serve as intermediate signals for a diverse set of cellular processes. [from NCI]

MedGen UID:
19914
Concept ID:
C0036522
Molecular Function
11.

Sodium chloride

A metal halide composed of sodium and chloride with sodium and chloride replacement capabilities. When depleted in the body, sodium must be replaced in order to maintain intracellular osmolarity, nerve conduction, muscle contraction and normal renal function. [from NCI]

MedGen UID:
11483
Concept ID:
C0037494
Biologically Active Substance; Inorganic Chemical; Pharmacologic Substance
12.

Mannitol

A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity. [from MeSH]

MedGen UID:
7462
Concept ID:
C0024730
Organic Chemical; Pharmacologic Substance
13.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Organic Chemical; Pharmacologic Substance
14.

Blood clotting factor

Endogenous substances, usually proteins, that are involved in the blood coagulation process. [from MeSH]

MedGen UID:
605
Concept ID:
C0005789
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
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