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Items: 8

1.

Multiple myeloma

Multiple myeloma is a neoplastic plasma cell disorder characterized by clonal proliferation of malignant plasma cells in the bone marrow microenvironment, monoclonal protein in the blood or urine, and associated organ dysfunction (Palumbo and Anderson, 2011). [from OMIM]

MedGen UID:
10122
Concept ID:
C0026764
Neoplastic Process
2.

Glomerulonephritis

Inflammation of the renal glomeruli. [from HPO]

MedGen UID:
6616
Concept ID:
C0017658
Disease or Syndrome
3.

Amyloidosis

Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should. . There are three main types of amyloidosis:. -Primary - with no known cause. -Secondary - caused by another disease, including some types of cancer. -Familial - passed down through genes. Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.  [from MedlinePlus]

MedGen UID:
272
Concept ID:
C0002726
Disease or Syndrome
4.

progressive

MedGen UID:
851455
Concept ID:
CN232553
Finding
5.

Multiple myeloma

A malignant plasma cell tumor growing within soft tissue or within the skeleton. [from HPO]

MedGen UID:
505979
Concept ID:
CN005898
Finding
6.

Rapidly progressive glomerulonephritis

Glomerulonephritis characterized by a rapid decrease in the glomerular filtration rate, typically a 50% reduction occurring over days to weeks. [from NCI_NICHD]

MedGen UID:
113155
Concept ID:
C0221239
Disease or Syndrome
7.

AL amyloidosis

A plasma cell neoplasm that secretes an abnormal immunoglobulin, which deposits in tissues and forms a beta-pleated sheet structure that binds Congo red dye with characteristic birefringence. (WHO, 2001) [from NCI]

MedGen UID:
75674
Concept ID:
C0268381
Disease or Syndrome
8.

Renal amyloidosis

A form of amyloidosis that affects the kidney. [from HPO]

MedGen UID:
120633
Concept ID:
C0268382
Disease or Syndrome
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