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Infection by Dracunculus medinensis

MedGen UID:
41653
Concept ID:
C0013100
Disease or Syndrome
Synonyms: Disease, Guinea Worm; Diseases, Guinea Worm; Dracunculiases; Dracunculiasis; Dracunculoses; Dracunculosis; Guinea Worm Disease; Guinea Worm Diseases; Guinea Worm Infection; Infection, Guinea Worm; Worm Disease, Guinea
SNOMED CT: Infection by Dracunculus medinensis (396334002); Dracontiasis - guinea-worm (396334002); Dracontiasis (396334002); Dracunculosis (396334002); Guinea-worm infection (396334002); Guinea worm disease (396334002); Dracunculiasis (396334002); Infection caused by Dracunculus medinensis (396334002)
 
Orphanet: ORPHA231

Definition

An infection that is caused by Dracunculus medinensis, which is acquired by drinking water contaminated with infected copepods. The larvae enter the body through the intestine. Signs and symptoms include pain, edema, blisters, and ulcers, with the adult female worm potentially emerging from the skin over time. [from NCI_NICHD]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfection by Dracunculus medinensis
Follow this link to review classifications for Infection by Dracunculus medinensis in Orphanet.

Recent clinical studies

Etiology

Greenwood B, Greenwood A, Bradley A
Trop Med Int Health 2017 May;22(5):558-566. Epub 2017 Apr 5 doi: 10.1111/tmi.12855. PMID: 28196301Free PMC Article
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep 2011 Oct 28;60(42):1450-3. PMID: 22031217
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep 2011 Jun 10;60(22):744-8. PMID: 21659983
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep 2010 Oct 1;59(38):1239-42. PMID: 20881936
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep 2009 Oct 16;58(40):1123-5. PMID: 19834453

Diagnosis

Barry SK, Schucany WG
J Radiol Case Rep 2012 Nov;6(11):29-33. Epub 2012 Nov 1 doi: 10.3941/jrcr.v6i11.1137. PMID: 23372866Free PMC Article
Eberhard ML, Ruiz-Tiben E, Korkor AS, Roy SL, Downs P
Am J Trop Med Hyg 2010 Dec;83(6):1348-51. doi: 10.4269/ajtmh.2010.10-0475. PMID: 21118947Free PMC Article
Hakim FA, Khan NN
Saudi Med J 2007 Sep;28(9):1438-40. PMID: 17768477
Sing A, Wienert P, Sabisch P, Heesemann J, Rinecker H
Clin Infect Dis 1998 Dec;27(6):1361, 1508-9. PMID: 9868641
Bloch P, Simonsen PE
Acta Trop 1998 Jun 15;70(1):73-86. PMID: 9707366

Therapy

Toda M, Njeru I, Zurovac D, O-Tipo S, Kareko D, Mwau M, Morita K
Emerg Infect Dis 2016 Apr;22(4):711-5. doi: 10.3201/eid2204.151459. PMID: 26981628Free PMC Article
Miri ES, Hopkins DR, Ruiz-Tiben E, Keana AS, Withers PC Jr, Anagbogu IN, Sadiq LK, Kale OO, Edungbola LD, Braide EI, Ologe JO, Ityonzughul C
Am J Trop Med Hyg 2010 Aug;83(2):215-25. doi: 10.4269/ajtmh.2010.10-0140. PMID: 20682859Free PMC Article
Njepuome NA, Hopkins DR, Richards FO Jr, Anagbogu IN, Pearce PO, Jibril MM, Okoronkwo C, Sofola OT, Withers PC Jr, Ruiz-Tiben E, Miri ES, Eigege A, Emukah EC, Nwobi BC, Jiya JY
Am J Trop Med Hyg 2009 May;80(5):691-8. PMID: 19407107
Wkly Epidemiol Rec 2001 Apr 13;76(15):112-6. PMID: 11392081
Hopkins DR, Ruiz-Tiben E, Ruebush TK, Diallo N, Agle A, Withers PC Jr
Am J Trop Med Hyg 2000 Feb;62(2):163-8. PMID: 10813467

Prognosis

Hopkins DR, Ruiz-Tiben E, Eberhard ML, Roy SL; Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep 2014 Nov 21;63(46):1050-4. PMID: 25412061
Centers for Disease Control and Prevention.
MMWR Morb Mortal Wkly Rep 2013 Oct 25;62(42):829-33. PMID: 24153313
Centers for Disease Control and Prevention.
MMWR Morb Mortal Wkly Rep 2012 Oct 26;61(42):854-7. PMID: 23095954
Richards FO, Ruiz-Tiben E, Hopkins DR
Vaccine 2011 Dec 30;29 Suppl 4:D86-90. Epub 2011 Dec 18 doi: 10.1016/j.vaccine.2011.07.115. PMID: 22185836
Centers for Disease Control and Prevention (CDC).
MMWR Morb Mortal Wkly Rep 2010 Oct 1;59(38):1239-42. PMID: 20881936

Clinical prediction guides

Knopp S, Amegbo IK, Hamm DM, Schulz-Key H, Banla M, Soboslay PT
Trans R Soc Trop Med Hyg 2008 Mar;102(3):277-83. Epub 2008 Feb 6 doi: 10.1016/j.trstmh.2007.12.003. PMID: 18258273
Anosike JC, Nwoke BE, Dozie I, Thofern UA, Okere AN, Njoku-Tony R, Nwosu DC, Oguwuike UT, Dike MC, Alozie JI, Okugun GR, Ajero CM, Onyirioha CU, Ezike MN, Ogbusu FI, Ajayi EG
Int J Hyg Environ Health 2003 Oct;206(6):591-6. doi: 10.1078/1438-4639-00246. PMID: 14626906
Bloch P, Simonsen PE
Am J Trop Med Hyg 1998 Dec;59(6):985-90. PMID: 9886210
Bloch P, Simonsen PE
Am J Trop Med Hyg 1998 Dec;59(6):978-84. PMID: 9886209
Bloch P, Simonsen PE, Vennervald BJ
J Helminthol 1993 Mar;67(1):37-48. PMID: 8509617

Recent systematic reviews

Berkowitz AL, Raibagkar P, Pritt BS, Mateen FJ
J Neurol Sci 2015 Feb 15;349(1-2):20-32. Epub 2015 Jan 9 doi: 10.1016/j.jns.2015.01.001. PMID: 25623803
Kappagoda S, Ioannidis JP
Bull World Health Organ 2014 May 1;92(5):356-366C. Epub 2014 Mar 13 doi: 10.2471/BLT.13.129601. PMID: 24839325Free PMC Article
Kappagoda S, Ioannidis JP
BMJ 2012 Oct 22;345:e6512. PMID: 23089149Free PMC Article
Reddy M, Gill SS, Kalkar SR, Wu W, Anderson PJ, Rochon PA
JAMA 2007 Oct 24;298(16):1911-24. doi: 10.1001/jama.298.16.1911. PMID: 17954542

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