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Items: 5

1.

Peripheral T-cell lymphoma (clinical)

A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment. [from MeSH]

MedGen UID:
38240
Concept ID:
C0079774
Neoplastic Process
2.

T-cell lymphoma

A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes. [from MeSH]

MedGen UID:
86957
Concept ID:
C0079772
Neoplastic Process
3.

Anaplastic large-cell lymphoma

A peripheral (mature) T-cell lymphoma, consisting of usually large anaplastic, CD30 positive cells. The majority of cases are positive for the anaplastic large cell lymphoma (ALK) protein. The most frequently seen genetic alteration is a t(2;5) translocation. Majority of patients present with advanced disease. The most important prognostic indicator is ALK positivity, which has been associated with a favorable prognosis. (WHO, 2001) [from NCI]

MedGen UID:
61533
Concept ID:
C0206180
Neoplastic Process
4.

Leukemia

A cancer of the blood and bone marrow characterized by an abnormal proliferation of leukocytes. [from HPO]

MedGen UID:
9725
Concept ID:
C0023418
Neoplastic Process
5.

Dendritic Cell Tumor, Not Otherwise Specified

A dendritic cell neoplasm that does not fall into well-defined categories or shows hybrid features. [from NCI]

MedGen UID:
226984
Concept ID:
C1301364
Neoplastic Process
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