Format

Send to:

Choose Destination

Links from PubMed

gabapentin

MedGen UID:
16535
Concept ID:
C0060926
Organic Chemical; Pharmacologic Substance
Synonyms: 1-(aminomethyl)cyclohexaneacetic acid; Convalis
SNOMED CT: Gabapentin (386845007); Gabapentin (108402001)
 

Definition

A synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant activity. Although its exact mechanism of action is unknown, gabapentin appears to inhibit excitatory neuron activity. This agent also exhibits analgesic properties. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38402&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38402&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1108" NCI Thesaurus) [from PDQ]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVgabapentin

Recent clinical studies

Etiology

Wang J, Zhu Y
J Dermatolog Treat 2017 Feb;28(1):65-77. Epub 2016 Nov 1 doi: 10.3109/09546634.2016.1163315. PMID: 27798973
Sanders JG, Dawes PJ
Otolaryngol Head Neck Surg 2016 Dec;155(6):893-903. Epub 2016 Jul 26 doi: 10.1177/0194599816659042. PMID: 27459955
Yılmaz Çakirgöz M, Demirel İ, Duran E, Özer AB, Hancı V, Türkmen ÜA, Aydın A, Ersoy A, Büyükyıldırım A
Braz J Anesthesiol 2016 Jul-Aug;66(4):356-62. Epub 2015 Oct 20 doi: 10.1016/j.bjane.2014.11.014. PMID: 27343784
Nofal E, Farag F, Nofal A, Eldesouky F, Alkot R, Abdelkhalik Z
J Dermatolog Treat 2016 Nov;27(6):515-519. Epub 2016 Apr 4 doi: 10.3109/09546634.2016.1161161. PMID: 27043168
Sarıtaş TB, Korkmaz M, Sevimli A, Sarıtaş ZK
Int Wound J 2016 Oct;13(5):748-53. Epub 2014 Oct 28 doi: 10.1111/iwj.12364. PMID: 25348659

Diagnosis

Han C, Li XD, Jiang HQ, Ma JX, Ma XL
Medicine (Baltimore) 2016 Jun;95(23):e3883. doi: 10.1097/MD.0000000000003883. PMID: 27281103Free PMC Article
Parsons KA, Derkits ME
Am J Health Syst Pharm 2016 May 15;73(10):631-4. doi: 10.2146/ajhp150136. PMID: 27147215
Ozturk S, Ucler N, Hergunsel OB, Gulkesen A, Kaplan M
Clin Neuropharmacol 2016 May-Jun;39(3):140-3. doi: 10.1097/WNF.0000000000000145. PMID: 26992157
Bastiaens L, Galus J, Mazur C
Psychiatr Q 2016 Dec;87(4):763-767. doi: 10.1007/s11126-016-9421-7. PMID: 26887855
North JM, Hong KS, Rauck RL
Pain Pract 2016 Jul;16(6):720-9. Epub 2015 Jun 8 doi: 10.1111/papr.12319. PMID: 26059271

Therapy

Wang J, Zhu Y
J Dermatolog Treat 2017 Feb;28(1):65-77. Epub 2016 Nov 1 doi: 10.3109/09546634.2016.1163315. PMID: 27798973
Choi MS, Jeon H, Kim HS, Jang BH, Lee YH, Park HS, Kim H, Jin DC
Hemodial Int 2017 Jan;21(1):E4-E8. Epub 2016 Jul 8 doi: 10.1111/hdi.12458. PMID: 27389284
Sanders JG, Dawes PJ
Otolaryngol Head Neck Surg 2016 Dec;155(6):893-903. Epub 2016 Jul 26 doi: 10.1177/0194599816659042. PMID: 27459955
Nofal E, Farag F, Nofal A, Eldesouky F, Alkot R, Abdelkhalik Z
J Dermatolog Treat 2016 Nov;27(6):515-519. Epub 2016 Apr 4 doi: 10.3109/09546634.2016.1161161. PMID: 27043168
Kataoka T, Kiyota N, Shimada T, Funakoshi Y, Chayahara N, Toyoda M, Fujiwara Y, Nibu K, Komori T, Sasaki R, Mukohara T, Minami H
Auris Nasus Larynx 2016 Dec;43(6):677-84. Epub 2016 Mar 15 doi: 10.1016/j.anl.2016.02.012. PMID: 26992271

Prognosis

Khezri MB, Nasseh N, Soltanian G
Medicine (Baltimore) 2017 Apr;96(15):e6545. doi: 10.1097/MD.0000000000006545. PMID: 28403084Free PMC Article
Ozturk S, Ucler N, Hergunsel OB, Gulkesen A, Kaplan M
Clin Neuropharmacol 2016 May-Jun;39(3):140-3. doi: 10.1097/WNF.0000000000000145. PMID: 26992157
Doleman B, Heinink TP, Read DJ, Faleiro RJ, Lund JN, Williams JP
Anaesthesia 2015 Oct;70(10):1186-204. Epub 2015 Aug 24 doi: 10.1111/anae.13179. PMID: 26300519
Boyle Y, Fernando D, Kurz H, Miller SR, Zucchetto M, Storey J
Pain 2014 Dec;155(12):2510-6. Epub 2014 Sep 10 doi: 10.1016/j.pain.2014.09.003. PMID: 25218827
Dolgun H, Turkoglu E, Kertmen H, Gurer B, Yilmaz ER, Comoglu SS, Sekerci Z
Neurol Res 2014 Dec;36(12):1080-5. Epub 2014 Jun 18 doi: 10.1179/1743132814Y.0000000404. PMID: 24938318

Clinical prediction guides

Wang J, Zhu Y
J Dermatolog Treat 2017 Feb;28(1):65-77. Epub 2016 Nov 1 doi: 10.3109/09546634.2016.1163315. PMID: 27798973
Sanders JG, Dawes PJ
Otolaryngol Head Neck Surg 2016 Dec;155(6):893-903. Epub 2016 Jul 26 doi: 10.1177/0194599816659042. PMID: 27459955
Yılmaz Çakirgöz M, Demirel İ, Duran E, Özer AB, Hancı V, Türkmen ÜA, Aydın A, Ersoy A, Büyükyıldırım A
Braz J Anesthesiol 2016 Jul-Aug;66(4):356-62. Epub 2015 Oct 20 doi: 10.1016/j.bjane.2014.11.014. PMID: 27343784
Kataoka T, Kiyota N, Shimada T, Funakoshi Y, Chayahara N, Toyoda M, Fujiwara Y, Nibu K, Komori T, Sasaki R, Mukohara T, Minami H
Auris Nasus Larynx 2016 Dec;43(6):677-84. Epub 2016 Mar 15 doi: 10.1016/j.anl.2016.02.012. PMID: 26992271
Sarıtaş TB, Korkmaz M, Sevimli A, Sarıtaş ZK
Int Wound J 2016 Oct;13(5):748-53. Epub 2014 Oct 28 doi: 10.1111/iwj.12364. PMID: 25348659

Recent systematic reviews

Peng C, Li C, Qu J, Wu D
Medicine (Baltimore) 2017 Apr;96(15):e6463. doi: 10.1097/MD.0000000000006463. PMID: 28403075Free PMC Article
Cooper TE, Derry S, Wiffen PJ, Moore RA
Cochrane Database Syst Rev 2017 Jan 3;1:CD012188. doi: 10.1002/14651858.CD012188.pub2. PMID: 28045473
Wang J, Zhu Y
J Dermatolog Treat 2017 Feb;28(1):65-77. Epub 2016 Nov 1 doi: 10.3109/09546634.2016.1163315. PMID: 27798973
Sanders JG, Dawes PJ
Otolaryngol Head Neck Surg 2016 Dec;155(6):893-903. Epub 2016 Jul 26 doi: 10.1177/0194599816659042. PMID: 27459955
Fabritius ML, Geisler A, Petersen PL, Nikolajsen L, Hansen MS, Kontinen V, Hamunen K, Dahl JB, Wetterslev J, Mathiesen O
Acta Anaesthesiol Scand 2016 Oct;60(9):1188-208. Epub 2016 Jul 18 doi: 10.1111/aas.12766. PMID: 27426431

Supplemental Content

Table of contents

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...
    Support Center