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Glutamine

MedGen UID:
5329
Concept ID:
C0017797
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
Synonyms: L Glutamine; L-Glutamine
SNOMED CT: Gln - Glutamine (25761002); Glutamine (412421007); Levoglutamide (25761002); L-Glutamine (25761002); L-Glutamine (412421007); Levoglutamide (412421007); Glutamine (25761002)
 

Definition

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlutamine

Recent clinical studies

Etiology

Sands S, Ladas EJ, Kelly KM, Weiner M, Lin M, Ndao DH, Dave A, Vahdat LT, Bender JG
Support Care Cancer 2017 Mar;25(3):701-708. Epub 2016 Nov 9 doi: 10.1007/s00520-016-3441-6. PMID: 27830395Free PMC Article
Thakkar KN, Rösler L, Wijnen JP, Boer VO, Klomp DW, Cahn W, Kahn RS, Neggers SF
Biol Psychiatry 2017 Mar 15;81(6):525-535. Epub 2016 Apr 19 doi: 10.1016/j.biopsych.2016.04.007. PMID: 27316853
Buter H, Koopmans M, Kemperman R, Jekel L, Boerma C
J Cardiothorac Surg 2016 Nov 25;11(1):155. doi: 10.1186/s13019-016-0549-1. PMID: 27884211Free PMC Article
Martins HA, Sehaber CC, Hermes-Uliana C, Mariani FA, Guarnier FA, Vicentini GE, Bossolani GD, Jussani LA, Lima MM, Bazotte RB, Zanoni JN
Amino Acids 2016 Dec;48(12):2773-2784. Epub 2016 Aug 18 doi: 10.1007/s00726-016-2313-1. PMID: 27539646
Bhutia YD, Ganapathy V
Biochim Biophys Acta 2016 Oct;1863(10):2531-9. Epub 2015 Dec 24 doi: 10.1016/j.bbamcr.2015.12.017. PMID: 26724577Free PMC Article

Diagnosis

Tan HWS, Sim AYL, Long YC
Nat Commun 2017 Aug 24;8(1):338. doi: 10.1038/s41467-017-00369-y. PMID: 28835610Free PMC Article
Torres-Santiago L, Mauras N, Hossain J, Weltman AL, Darmaun D
Nutrition 2017 Feb;34:1-6. Epub 2016 Sep 20 doi: 10.1016/j.nut.2016.09.003. PMID: 28063503Free PMC Article
Sands S, Ladas EJ, Kelly KM, Weiner M, Lin M, Ndao DH, Dave A, Vahdat LT, Bender JG
Support Care Cancer 2017 Mar;25(3):701-708. Epub 2016 Nov 9 doi: 10.1007/s00520-016-3441-6. PMID: 27830395Free PMC Article
Tran TQ, Lowman XH, Reid MA, Mendez-Dorantes C, Pan M, Yang Y, Kong M
Oncogene 2017 Apr 6;36(14):1991-2001. Epub 2016 Oct 10 doi: 10.1038/onc.2016.360. PMID: 27721412Free PMC Article
Nienaber A, Dolman RC, van Graan AE, Blaauw R
Nutr J 2016 Aug 2;15(1):73. doi: 10.1186/s12937-016-0188-3. PMID: 27485319Free PMC Article

Therapy

Damiani C, Colombo R, Gaglio D, Mastroianni F, Pescini D, Westerhoff HV, Mauri G, Vanoni M, Alberghina L
PLoS Comput Biol 2017 Sep;13(9):e1005758. Epub 2017 Sep 28 doi: 10.1371/journal.pcbi.1005758. PMID: 28957320Free PMC Article
Sands S, Ladas EJ, Kelly KM, Weiner M, Lin M, Ndao DH, Dave A, Vahdat LT, Bender JG
Support Care Cancer 2017 Mar;25(3):701-708. Epub 2016 Nov 9 doi: 10.1007/s00520-016-3441-6. PMID: 27830395Free PMC Article
Buter H, Koopmans M, Kemperman R, Jekel L, Boerma C
J Cardiothorac Surg 2016 Nov 25;11(1):155. doi: 10.1186/s13019-016-0549-1. PMID: 27884211Free PMC Article
Martins HA, Sehaber CC, Hermes-Uliana C, Mariani FA, Guarnier FA, Vicentini GE, Bossolani GD, Jussani LA, Lima MM, Bazotte RB, Zanoni JN
Amino Acids 2016 Dec;48(12):2773-2784. Epub 2016 Aug 18 doi: 10.1007/s00726-016-2313-1. PMID: 27539646
Brinkmann SJ, Buijs N, Vermeulen MA, Oosterink E, Schierbeek H, Beishuizen A, de Vries JP, Wisselink W, van Leeuwen PA
Am J Physiol Renal Physiol 2016 Sep 1;311(3):F567-75. Epub 2016 May 18 doi: 10.1152/ajprenal.00340.2015. PMID: 27194717

Prognosis

Damiani C, Colombo R, Gaglio D, Mastroianni F, Pescini D, Westerhoff HV, Mauri G, Vanoni M, Alberghina L
PLoS Comput Biol 2017 Sep;13(9):e1005758. Epub 2017 Sep 28 doi: 10.1371/journal.pcbi.1005758. PMID: 28957320Free PMC Article
Thakkar KN, Rösler L, Wijnen JP, Boer VO, Klomp DW, Cahn W, Kahn RS, Neggers SF
Biol Psychiatry 2017 Mar 15;81(6):525-535. Epub 2016 Apr 19 doi: 10.1016/j.biopsych.2016.04.007. PMID: 27316853
Buter H, Koopmans M, Kemperman R, Jekel L, Boerma C
J Cardiothorac Surg 2016 Nov 25;11(1):155. doi: 10.1186/s13019-016-0549-1. PMID: 27884211Free PMC Article
Nienaber A, Dolman RC, van Graan AE, Blaauw R
Nutr J 2016 Aug 2;15(1):73. doi: 10.1186/s12937-016-0188-3. PMID: 27485319Free PMC Article
Mundi MS, Shah M, Hurt RT
Nutr Clin Pract 2016 Aug;31(4):445-50. Epub 2016 May 31 doi: 10.1177/0884533616651318. PMID: 27246308

Clinical prediction guides

Damiani C, Colombo R, Gaglio D, Mastroianni F, Pescini D, Westerhoff HV, Mauri G, Vanoni M, Alberghina L
PLoS Comput Biol 2017 Sep;13(9):e1005758. Epub 2017 Sep 28 doi: 10.1371/journal.pcbi.1005758. PMID: 28957320Free PMC Article
Liu Z, Wang J, Li Y, Fan J, Chen L, Xu R
Tumour Biol 2017 Feb;39(2):1010428317691429. doi: 10.1177/1010428317691429. PMID: 28218035
Sands S, Ladas EJ, Kelly KM, Weiner M, Lin M, Ndao DH, Dave A, Vahdat LT, Bender JG
Support Care Cancer 2017 Mar;25(3):701-708. Epub 2016 Nov 9 doi: 10.1007/s00520-016-3441-6. PMID: 27830395Free PMC Article
Thakkar KN, Rösler L, Wijnen JP, Boer VO, Klomp DW, Cahn W, Kahn RS, Neggers SF
Biol Psychiatry 2017 Mar 15;81(6):525-535. Epub 2016 Apr 19 doi: 10.1016/j.biopsych.2016.04.007. PMID: 27316853
Buter H, Koopmans M, Kemperman R, Jekel L, Boerma C
J Cardiothorac Surg 2016 Nov 25;11(1):155. doi: 10.1186/s13019-016-0549-1. PMID: 27884211Free PMC Article

Recent systematic reviews

Moe-Byrne T, Brown JV, McGuire W
Cochrane Database Syst Rev 2016 Apr 18;4:CD001457. doi: 10.1002/14651858.CD001457.pub6. PMID: 27089158
Oliveira GP, de Abreu MG, Pelosi P, Rocco PR
Nutrients 2016 Feb 4;8(2):76. doi: 10.3390/nu8020076. PMID: 26861387Free PMC Article
Akobeng AK, Elawad M, Gordon M
Cochrane Database Syst Rev 2016 Feb 8;2:CD007348. doi: 10.1002/14651858.CD007348.pub2. PMID: 26853855
Sayles C, Hickerson SC, Bhat RR, Hall J, Garey KW, Trivedi MV
Nutr Clin Pract 2016 Apr;31(2):171-9. Epub 2015 Oct 27 doi: 10.1177/0884533615611857. PMID: 26507188
Heyland DK, Elke G, Cook D, Berger MM, Wischmeyer PE, Albert M, Muscedere J, Jones G, Day AG; Canadian Critical Care Trials Group.
JPEN J Parenter Enteral Nutr 2015 May;39(4):401-9. Epub 2014 May 5 doi: 10.1177/0148607114529994. PMID: 24803474

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