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Items: 7

1.

Furriers lung

MedGen UID:
538594
Concept ID:
C0264476
Disease or Syndrome
2.

Coffee-workers lung

MedGen UID:
538589
Concept ID:
C0264468
Disease or Syndrome
3.

Malt-workers lung

MedGen UID:
510125
Concept ID:
C0155888
Disease or Syndrome
4.

Cheese-washers lung

MedGen UID:
507549
Concept ID:
C0007969
Disease or Syndrome
5.

Budesonide

A glucocorticoid used in the management of ASTHMA, the treatment of various skin disorders, and allergic RHINITIS. [from MeSH]

MedGen UID:
26513
Concept ID:
C0054201
Organic Chemical; Pharmacologic Substance
6.

Acetylcysteine

A synthetic N-acetyl derivative of the endogenous amino acid L-cysteine, a precursor of the antioxidant enzyme glutathione. Acetylcysteine regenerates liver stores of glutathione. This agent also reduces disulfide bonds in mucoproteins, resulting in liquification of mucus. Some evidence suggests that acetylcysteine may exert an anti-apoptotic effect due to its antioxidant activity, possibly preventing cancer cell development or growth. In addition, acetylcysteine has inhibited viral stimulation by reactive oxygen intermediates, thereby producing antiviral activity in HIV patients. (NCI04) [from NCI]

MedGen UID:
1285
Concept ID:
C0001047
Amino Acid, Peptide, or Protein; Pharmacologic Substance
7.

Phenethyl Isothiocyanate

An isothiocyanate found in cruciferous vegetables with chemopreventive and potential antitumor activities. Although the mechanism of action is unclear, phenethyl Isothiocyanate (PEITC) was shown to induce apoptosis in tumor cells, possibly mediated through its metabolic intermediates, reactive oxygen species (ROS). PEITC also is able to activate ERK and JNK signal transduction, which in turn induces expression of stress-responsive genes. Specifically, this agent has been shown to reactivate gene expression of a detoxification enzyme, glutathione S-transferase that is silenced in prostate carcinoma. [from NCI]

MedGen UID:
33016
Concept ID:
C0070558
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
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