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Items: 1 to 20 of 24

1.

Cetrorelix

Cetrorelix is a synthetic decapeptide which is structurally related to gonadotrophin-releasing hormone (luteinising-hormone releasing hormone). It acts as an LHRH antagonist. (from ASTA Medica) [from NCI]

MedGen UID:
60442
Concept ID:
C0209366
Amino Acid, Peptide, or Protein; Pharmacologic Substance
2.

Pituitary luteinizing hormone

A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity. [from MeSH]

MedGen UID:
6078
Concept ID:
C0023607
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
3.

Negative

An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure. [Note: Negative does not necessarily imply the complete absence of the specified item.].  [from HL7]

MedGen UID:
61377
Concept ID:
C0205160
Finding
4.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
5.

EGFR-related lung cancer

MedGen UID:
472093
Concept ID:
CN130014
Disease or Syndrome
6.

Proliferation

MedGen UID:
137720
Concept ID:
C0334094
Pathologic Function
7.

Neoplasm of the breast

Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Although breast cancer is much more common in women, this form of cancer can also develop in men. In both women and men, the most common form of breast cancer begins in cells lining the milk ducts (ductal cancer). In women, cancer can also develop in the glands that produce milk (lobular cancer). Most men have little or no lobular tissue, so lobular cancer in men is very rare.In its early stages, breast cancer usually does not cause pain and may exhibit no noticeable symptoms. As the cancer progresses, signs and symptoms can include a lump or thickening in or near the breast; a change in the size or shape of the breast; nipple discharge, tenderness, or retraction (turning inward); and skin irritation, dimpling, or scaliness. However, these changes can occur as part of many different conditions. Having one or more of these symptoms does not mean that a person definitely has breast cancer.In some cases, cancerous tumors can invade surrounding tissue and spread to other parts of the body. If breast cancer spreads, cancerous cells most often appear in the bones, liver, lungs, or brain. Tumors that begin at one site and then spread to other areas of the body are called metastatic cancers.A small percentage of all breast cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations. Hereditary breast cancers tend to develop earlier in life than noninherited (sporadic) cases, and new (primary) tumors are more likely to develop in both breasts. [from GTR]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
8.

Kryptocur

MedGen UID:
152057
Concept ID:
C0699450
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
9.

Dirigestran

MedGen UID:
152056
Concept ID:
C0699449
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
10.

Antineoplastic Hormonal/Endocrine Agent

Any agent that affects hormone levels and exerts antineoplastic effects. Antineoplastic hormonal/endocrine agents treat either hormone-dependent or hormone-sensitive cancers by modulating hormone levels and manipulating the endocrine system. [from NCI]

MedGen UID:
129191
Concept ID:
C0282559
Pharmacologic Substance
11.

Cystorelin

MedGen UID:
90223
Concept ID:
C0308762
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
12.

Factrel

MedGen UID:
86295
Concept ID:
C0306166
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
13.

Skin and Connective Tissue Diseases

A collective term for diseases of the skin and its appendages and of connective tissue. [from MeSH]

MedGen UID:
59786
Concept ID:
C0175166
Disease or Syndrome
14.

dermopathy

An abnormality of the skin. [from HPO]

MedGen UID:
20777
Concept ID:
C0037274
Disease or Syndrome
15.

Hormones, Hormone Substitutes, and Hormone Antagonists

A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists. [from MeSH]

MedGen UID:
6887
Concept ID:
C0019934
Pharmacologic Substance
16.

Gonadorelin

A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND. [from MeSH]

MedGen UID:
6079
Concept ID:
C0023610
Amino Acid, Peptide, or Protein; Hormone; Pharmacologic Substance
17.

Hormone antagonists

Chemical substances which inhibit the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. [from MeSH]

MedGen UID:
5614
Concept ID:
C0019927
Pharmacologic Substance
18.

Antineoplastic agent

A substance that inhibits the maturation, growth or spread of tumor cells. [from NCI]

MedGen UID:
1984
Concept ID:
C0003392
Organic Chemical; Pharmacologic Substance
19.

Disorder of breast

A non-neoplastic or neoplastic disorder that affects the breast. Representative examples of non-neoplastic disorders include fibrocystic disease, gynecomastia, and mastitis. Representative examples of neoplastic disorders include fibroadenoma, lobular neoplasia, carcinoma, lymphoma, and sarcoma. [from NCI]

MedGen UID:
652
Concept ID:
C0006145
Disease or Syndrome
20.

Cetrotide

MedGen UID:
182638
Concept ID:
C0939290
Organic Chemical; Pharmacologic Substance
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