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Items: 1 to 20 of 23

1.

Fatty Acid Metabolism Pathway

Fatty Acid Metabolism involves cellular biotransforming chemical modifications of fatty acids by enzymatic activity. [from NCI]

MedGen UID:
154548
Concept ID:
C0596563
Molecular Function
2.

Infection

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases. [from MeSH]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
3.

Metformin

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289) [from MeSH]

MedGen UID:
7578
Concept ID:
C0025598
Organic Chemical; Pharmacologic Substance
4.

Absence

MedGen UID:
739164
Concept ID:
C1689985
Anatomical Abnormality
5.

Able

MedGen UID:
721424
Concept ID:
C1299581
Finding
6.

Contraction

MedGen UID:
685783
Concept ID:
C1140999
Pathologic Function
7.

Profound

Having an extremely high degree of severity. For quantitative traits, a deviation of more than five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
615266
Concept ID:
C0439808
Qualitative Concept
8.

Withdrawal (dysfunction)

A social or emotional detachment, pathological retreat from objective reality, interpersonal contact and social involvement, as in some forms of schizophrenia, depression, or schizoid, avoidant, or schizotypal personality disorders. [from NCI]

MedGen UID:
442895
Concept ID:
C2825032
Mental or Behavioral Dysfunction
9.

Thyroid hormone plasma membrane transport defect

MedGen UID:
396060
Concept ID:
C1861101
Disease or Syndrome
10.

Mitochondrial inheritance

A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy). [from HPO]

MedGen UID:
165802
Concept ID:
C0887941
Genetic Function
11.

Vaccines

A Type of medicine that creates an immune protection without the recipient experiencing the disease.  [from HL7]

MedGen UID:
52963
Concept ID:
C0042210
Immunologic Factor; Pharmacologic Substance
12.

Oxidation

The process of oxidizing; the addition of oxygen to a compound accompanied by a loss of electrons. [from NCI]

MedGen UID:
18242
Concept ID:
C0030011
Molecular Function
13.

Antidiabetic preparation

Any substance used to reduce hyperglycemia or treat disorders associated with diabetes. Based on their mechanism of action, this class of agents can be classified to the following groups: directly acting insulomimetics, which activates insulin receptors; indirectly acting insulinomimetics, which increase insulin release such as sulfonylureas or which potentiate the effect of insulin such as metformin; those act directly on the metabolism of glucose such as inhibitors of glucosidases and inhibitors of aldose reductase. [from NCI]

MedGen UID:
183179
Concept ID:
C0935929
Pharmacologic Substance
14.

Glucophage

brand name of metformin an anti-diabetic drug [from CHV]

MedGen UID:
109212
Concept ID:
C0591573
Organic Chemical; Pharmacologic Substance
15.

Guanidine

A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. [from MeSH]

MedGen UID:
92574
Concept ID:
C0120446
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
16.

Gram-Positive Bacterial Infections

Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method. [from MeSH]

MedGen UID:
39283
Concept ID:
C0085426
Disease or Syndrome
17.

Bacterial Infections

Bacteria are living things that have only one cell. Under a microscope, they look like balls, rods, or spirals. They are so small that a line of 1,000 could fit across a pencil eraser. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. Bacteria are also used in making healthy foods like yogurt and cheese. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Antibiotics are the usual treatment. When you take antibiotics, follow the directions carefully. Each time you take antibiotics, you increase the chances that bacteria in your body will learn to resist them causing antibiotic resistance. Later, you could get or spread an infection that those antibiotics cannot cure. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
14012
Concept ID:
C0004623
Disease or Syndrome
18.

Listeriosis

Listeriosis is a foodborne illness caused by Listeria monocytogenes, bacteria found in soil and water. It can be in a variety of raw foods as well as in processed foods and foods made from unpasteurized milk. Listeria is unlike many other germs because it can grow even in the cold temperature of the refrigerator. . Symptoms include fever and chills, headache, upset stomach and vomiting. Treatment is with antibiotics. Anyone can get the illness. But it is most likely to affect pregnant women and unborn babies, older adults, and people with weak immune systems. To reduce your risk. -Use precooked and ready-to-eat foods as soon as you can . - Avoid raw milk and raw milk products. - Heat ready-to-eat foods and leftovers until they are steaming hot. - Wash fresh fruits and vegetables . - Avoid rare meat and refrigerated smoked seafood. Centers for Disease Control and Prevention.  [from MedlinePlus]

MedGen UID:
9788
Concept ID:
C0023860
Disease or Syndrome
19.

Hypoglycemic agent

Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends on your type of diabetes, your schedule, and your other health conditions. . With type 1 diabetes, your pancreas does not make insulin. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. If you have type 1 diabetes, you will need to take insulin. . Type 2 diabetes, the most common type, can start when the body doesn't use insulin as it should. If your body can't keep up with the need for insulin, you may need to take pills. Along with meal planning and physical activity, diabetes pills help people with type 2 diabetes or gestational diabetes keep their blood glucose levels on target. Several kinds of pills are available. Each works in a different way. Many people take two or three kinds of pills. Some people take combination pills. Combination pills contain two kinds of diabetes medicine in one tablet. Some people take pills and insulin. NIH: National Institute of Diabetes and Digestive and Kidney Diseases.  [from MedlinePlus]

MedGen UID:
6980
Concept ID:
C0020616
Pharmacologic Substance
20.

Biguanides

Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES. [from MeSH]

MedGen UID:
2239
Concept ID:
C0005382
Organic Chemical; Pharmacologic Substance
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