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Items: 4

1.

Quetiapine

A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors. [from NCI]

MedGen UID:
50077
Concept ID:
C0123091
Organic Chemical; Pharmacologic Substance
2.

Psychiatric

MedGen UID:
851585
Concept ID:
C1548428
Finding
3.

Insomnia

MedGen UID:
409589
Concept ID:
C1963237
Finding
4.

Insomnia

A sleep disorder characterized by difficulty in falling asleep and/or remaining asleep. [from NCI]

MedGen UID:
214589
Concept ID:
C0917801
Sign or Symptom
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