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Items: 8

1.

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated (Tse et al., 2009). Genetic Heterogeneity of Susceptibility to Nasopharyngeal Carcinoma NPCA1 maps to chromosome 4p. NPCA2 (161550) maps to chromosome 6p21. NPCA3 (617075) is associated with variation in the MST1R gene (600168) on chromosome 3p21. [from OMIM]

MedGen UID:
419909
Concept ID:
C2931822
Disease or Syndrome; Neoplastic Process
2.

Carcinoma

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas (NCI Thesaurus). [from HPO]

MedGen UID:
2867
Concept ID:
C0007097
Neoplastic Process
3.

Carcinoma

MedGen UID:
910818
Concept ID:
CN241453
Finding
4.

Mantle cell lymphoma

Mantle cell lymphoma is a rare form of malignant non-Hodgkin lymphoma (see this term) affecting B lymphocytes in the lymph nodes in a region called the ``mantle zone''. [from ORDO]

MedGen UID:
798955
Concept ID:
CN205223
Finding
5.

Hereditary leiomyomatosis and renal cell cancer

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is characterized by cutaneous leiomyomata (multiple or single in 76% of affected individuals), uterine leiomyomata (fibroids), and/or a single renal tumor. Cutaneous leiomyomata appear as skin-colored to light brown papules or nodules distributed over the trunk and extremities, and occasionally on the face, and appear at a mean age of 25 years, increasing in size and number with age. Uterine leiomyomata are present in almost all females with HLRCC and tend to be numerous and large; age at diagnosis ranges from 18 to 52 years, with most women experiencing irregular or heavy menstruation and pelvic pain. Renal tumors causing hematuria, lower back pain, and a palpable mass are usually unilateral, solitary, and aggressive and range from type 2 papillary to tubulo-papillary to collecting-duct carcinomas. They occur in about 10%-16% of individuals with HLRCC; the median age of detection is 44 years. [from GeneReviews]

MedGen UID:
353771
Concept ID:
C1708350
Neoplastic Process
6.

Neoplasm of the pharynx

A benign or malignant neoplasm that affects the nasopharynx, oropharynx, or hypopharynx. [from NCI]

MedGen UID:
45844
Concept ID:
C0031347
Neoplastic Process
7.

Head and Neck Neoplasms

A tumor (abnormal growth of tissue) of the head and neck region with origin in the lip, oral cavity, nasal cavity, paranasal sinuses, pharynx, or larynx. [from HPO]

MedGen UID:
6728
Concept ID:
C0018671
Neoplastic Process
8.

Nasopharyngeal Neoplasms

Tumors or cancer of the NASOPHARYNX. [from MeSH]

MedGen UID:
6526
Concept ID:
C0027439
Neoplastic Process
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