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Akinetic mutism

MedGen UID:
807952
Concept ID:
CN185151
Finding
 

Definition

Akinetic mutism is essentially characterized by a total absence of spontaneous behavior and speech occurring in the presence of preserved visual tracking. [from HPO]

Recent clinical studies

Etiology

Iwasaki Y, Mimuro M, Yoshida M, Kitamoto T, Hashizume Y
Eur J Neurol 2011 Jul;18(7):999-1002. Epub 2010 Aug 16 doi: 10.1111/j.1468-1331.2010.03185.x. PMID: 20722706
Yang CP, Huang WS, Shih HT, Lin CY, Lu MK, Kao CH, Hsieh TC, Huang KJ, Lee YH, Tsai CH
Clin Neurol Neurosurg 2007 Sep;109(7):602-6. Epub 2007 May 31 doi: 10.1016/j.clineuro.2007.04.012. PMID: 17543443
Satoh K, Shirabe S, Eguchi H, Tsujino A, Motomura M, Satoh A, Tsujihata M, Eguchi K
Dement Geriatr Cogn Disord 2007;23(6):372-81. Epub 2007 Mar 26 doi: 10.1159/000101339. PMID: 17389797
Caner H, Altinörs N, Benli S, Calişaneller T, Albayrak A
Surg Neurol 1999 Feb;51(2):181-4. PMID: 10029425
Karabacak NI, Ozturk G, Gucuyener K, Gokcora N, Gursel T
Childs Nerv Syst 1997 Oct;13(10):560-2. doi: 10.1007/s003810050138. PMID: 9403207

Diagnosis

Demirtas-Tatlidede A, Bahar SZ, Gurvit H
Cogn Behav Neurol 2013 Jun;26(2):59-62. doi: 10.1097/WNN.0b013e31829bd4f5. PMID: 23812168
Choi S, Lee SH, Kim ES, Eoh W
Br J Neurosurg 2013 Aug;27(4):529-31. Epub 2013 Mar 8 doi: 10.3109/02688697.2013.771140. PMID: 23472625
Naito K, Ueno H, Sekine M, Kanemitsu M, Ohshita T, Nakamura T, Yamawaki T, Matsumoto M
Intern Med 2012;51(2):205-9. Epub 2012 Jan 15 PMID: 22246492
Rebai RM, Houissa S, Mustapha ME, Azzouni H, Assaggaf S
J Neurol Surg A Cent Eur Neurosurg 2012 Sep;73(5):341-6. Epub 2012 Aug 1 doi: 10.1055/s-0032-1313632. PMID: 21445822
Sierra-Hidalgo F, Martínez-Salio A, Moreno-García S, de Pablo-Fernández E, Correas-Callero E, Ruiz-Morales J
Clin Neuropharmacol 2009 Sep-Oct;32(5):293-4. doi: 10.1097/WNF.0b013e3181a77fab. PMID: 19820432

Therapy

Rozen TD
NeuroRehabilitation 2012;30(4):329-32. doi: 10.3233/NRE-2012-0763. PMID: 22672948
Naito K, Ueno H, Sekine M, Kanemitsu M, Ohshita T, Nakamura T, Yamawaki T, Matsumoto M
Intern Med 2012;51(2):205-9. Epub 2012 Jan 15 PMID: 22246492
Rebai RM, Houissa S, Mustapha ME, Azzouni H, Assaggaf S
J Neurol Surg A Cent Eur Neurosurg 2012 Sep;73(5):341-6. Epub 2012 Aug 1 doi: 10.1055/s-0032-1313632. PMID: 21445822
Kim YW, Shin JC, An YS
Clin Neuropharmacol 2010 Jul;33(4):209-11. doi: 10.1097/WNF.0b013e3181dca948. PMID: 20661027
Sierra-Hidalgo F, Martínez-Salio A, Moreno-García S, de Pablo-Fernández E, Correas-Callero E, Ruiz-Morales J
Clin Neuropharmacol 2009 Sep-Oct;32(5):293-4. doi: 10.1097/WNF.0b013e3181a77fab. PMID: 19820432

Prognosis

Demirtas-Tatlidede A, Bahar SZ, Gurvit H
Cogn Behav Neurol 2013 Jun;26(2):59-62. doi: 10.1097/WNN.0b013e31829bd4f5. PMID: 23812168
Rozen TD
NeuroRehabilitation 2012;30(4):329-32. doi: 10.3233/NRE-2012-0763. PMID: 22672948
Iwasaki Y, Mimuro M, Yoshida M, Kitamoto T, Hashizume Y
Eur J Neurol 2011 Jul;18(7):999-1002. Epub 2010 Aug 16 doi: 10.1111/j.1468-1331.2010.03185.x. PMID: 20722706
Sierra-Hidalgo F, Martínez-Salio A, Moreno-García S, de Pablo-Fernández E, Correas-Callero E, Ruiz-Morales J
Clin Neuropharmacol 2009 Sep-Oct;32(5):293-4. doi: 10.1097/WNF.0b013e3181a77fab. PMID: 19820432
Yang CP, Huang WS, Shih HT, Lin CY, Lu MK, Kao CH, Hsieh TC, Huang KJ, Lee YH, Tsai CH
Clin Neurol Neurosurg 2007 Sep;109(7):602-6. Epub 2007 May 31 doi: 10.1016/j.clineuro.2007.04.012. PMID: 17543443

Clinical prediction guides

Demirtas-Tatlidede A, Bahar SZ, Gurvit H
Cogn Behav Neurol 2013 Jun;26(2):59-62. doi: 10.1097/WNN.0b013e31829bd4f5. PMID: 23812168
Iwasaki Y, Mimuro M, Yoshida M, Kitamoto T, Hashizume Y
Eur J Neurol 2011 Jul;18(7):999-1002. Epub 2010 Aug 16 doi: 10.1111/j.1468-1331.2010.03185.x. PMID: 20722706
Naccache L, Obadia M, Crozier S, Detante O, Guillerm C, Bonneville F, Dormont D, Willer JC, Samson Y
Brain Res Cogn Brain Res 2004 Apr;19(2):202-5. doi: 10.1016/j.cogbrainres.2003.12.002. PMID: 15019716
Kotchoubey B, Schneck M, Lang S, Birbaumer N
Neurophysiol Clin 2003 Feb;33(1):23-30. PMID: 12711129
Karabacak NI, Ozturk G, Gucuyener K, Gokcora N, Gursel T
Childs Nerv Syst 1997 Oct;13(10):560-2. doi: 10.1007/s003810050138. PMID: 9403207

Recent systematic reviews

Vizcarra JA, Lang AE, Sethi KD, Espay AJ
Mov Disord 2015 Jun;30(7):886-94. Epub 2015 May 21 doi: 10.1002/mds.26263. PMID: 25997420Free PMC Article
Heckmann JG, Lang CJ, Kindler K, Huk W, Erbguth FJ, Neundörfer B
Crit Care Med 2000 May;28(5):1621-5. PMID: 10834723
Müller U, von Cramon DY
Prog Neuropsychopharmacol Biol Psychiatry 1994 Nov;18(7):1103-20. PMID: 7846283

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