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Items: 1 to 20 of 59

1.

Ibuprofen

A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis. [from MeSH]

MedGen UID:
9394
Concept ID:
C0020740
Organic Chemical; Pharmacologic Substance
2.

Alzheimer disease

MedGen UID:
1461959
Concept ID:
CN807353
Disease or Syndrome
3.

Alzheimer disease

Alzheimer disease (AD) is characterized by dementia that typically begins with subtle and poorly recognized failure of memory and slowly becomes more severe and, eventually, incapacitating. Other common findings include confusion, poor judgment, language disturbance, agitation, withdrawal, and hallucinations. Occasionally, seizures, Parkinsonian features, increased muscle tone, myoclonus, incontinence, and mutism occur. Death usually results from general inanition, malnutrition, and pneumonia. The typical clinical duration of the disease is eight to ten years, with a range from one to 25 years. Approximately 25% of all AD is familial (i.e., =2 persons in a family have AD) of which approximately 95% is late onset (age >60-65 years) and 5% is early onset (age <65 years). [from OMIM]

MedGen UID:
1853
Concept ID:
C0002395
Disease or Syndrome
4.

Course of illness

The worsening of a disease over time. [from NCI]

MedGen UID:
116631
Concept ID:
C0242656
Pathologic Function
5.

Dementia

MedGen UID:
99229
Concept ID:
C0497327
Finding; Mental or Behavioral Dysfunction
6.

Mental deterioration

MedGen UID:
66713
Concept ID:
C0234985
Mental or Behavioral Dysfunction
7.

Analgesics, Anti-Inflammatory

MedGen UID:
8050
Concept ID:
C0002773
Pharmacologic Substance
8.

Flurbiprofen

A derivative of propionic acid, and a phenylalkanoic acid derivative of non-steroidal antiinflammatory drugs (NSAIDs) with analgesic, antiinflammatory and antipyretic effects. Flurbiprofen non-selectively binds to and inhibits cyclooxygenase (COX). This results in a reduction of arachidonic acid conversion into prostaglandins that are involved in the regulation of pain, inflammation and fever. This NSAID also inhibits carbonic anhydrase, thereby reducing the production of hydrogen and bicarbonate ions. Upon ocular administration, flurbiprofen may reduce bicarbonate ion concentrations leading to a decrease in the production of aqueous humor, thereby lowering intraocular pressure. [from NCI]

MedGen UID:
4747
Concept ID:
C0016377
Organic Chemical; Pharmacologic Substance
9.

Peroxisome biogenesis disorder, complementation group R

MedGen UID:
1462842
Concept ID:
CN806929
Disease or Syndrome
10.

Dementia

MedGen UID:
1462717
Concept ID:
CN807171
Finding
11.

Mini-mental state examination score

MedGen UID:
755403
Concept ID:
C2960235
Finding
12.

Carrier status

MedGen UID:
623027
Concept ID:
C0449439
Finding
13.

Mental state finding

MedGen UID:
548631
Concept ID:
C0278060
Finding
14.

Moderate

Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
525853
Concept ID:
C0205081
Qualitative Concept
15.

Alzheimer disease

MedGen UID:
505259
Concept ID:
CN002282
Finding
16.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
17.

Peripheral

On or near an edge or constituting an outer boundary; the outer area. [from NCI]

MedGen UID:
59959
Concept ID:
C0205100
Spatial Concept
18.

Neurocognitive disorder

A disorder characterised by a decline primarily in intellectual function due to disease of the brain caused by a variety of acquired conditions such as cerebrovascular disease, Alzheimer's disease, infections, adverse drug reactions and trauma. [from SNOMEDCT_US]

MedGen UID:
873945
Concept ID:
C4041080
Mental or Behavioral Dysfunction
19.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
20.

Rufen

MedGen UID:
195842
Concept ID:
C0699206
Organic Chemical; Pharmacologic Substance
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