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Items: 2

1.

Pilocarpine

A natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. When applied topically to eyes, this agent stimulates the sphincter pupillae to contract, resulting in miosis; stimulates the ciliary muscle to contract, resulting in spasm of accommodation; and may cause a transitory rise in intraocular pressure followed by a more persistent fall due to opening of the trabecular meshwork and an increase in the outflow of aqueous humor. [from NCI]

MedGen UID:
19312
Concept ID:
C0031923
Organic Chemical; Pharmacologic Substance
2.

Status epilepticus

A life-threatening situation in which the brain is in a continuous state of seizure. [from NCI]

MedGen UID:
11586
Concept ID:
C0038220
Disease or Syndrome

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