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Items: 13

1.

Trypsin

A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4. [from MeSH]

MedGen UID:
21715
Concept ID:
C0041236
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
2.

Pefabloc

MedGen UID:
76504
Concept ID:
C0282730
Organic Chemical; Pharmacologic Substance
3.

Pancreatitis

INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis. [from MeSH]

MedGen UID:
14586
Concept ID:
C0030305
Disease or Syndrome
4.

Indicated

MedGen UID:
731837
Concept ID:
C1444656
Finding
5.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
6.

Digestive enzyme

MedGen UID:
639413
Concept ID:
C0544420
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
7.

Inflammatory Response

A part of innate immunity, the Inflammatory Response occurs when injured tissues induce release of vasodilatory, opsonizing, and chemotactic mediators that attract macrophages and leukocytes to phagocytize and destroy foreign substances; dilate local blood vessels increasing local blood flow; increase capillary permeability; produce edematous swelling; and induce pain. Plasma- and cell-derived inflammatory mediators include Prostaglandins, Leukotrines, Cytokines, Lymphokines, Monokines, PAF, Histamine, Bradykinin, Complement, and Interferons. [from NCI]

MedGen UID:
218869
Concept ID:
C1155266
Pathologic Function
8.

Mutant

An altered form of an individual, organism, population, or genetic character that differs from the corresponding wild type due to one or more alterations (mutations). [from NCI]

MedGen UID:
109303
Concept ID:
C0596988
Cell or Molecular Dysfunction
9.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
10.

Amino acid

Any organic compounds containing amino (-NH2) and carboxyl (-COOH) groups. In biochemistry, used to refer to the twenty-plus L-alpha-amino acids found in proteins. [from NCI]

MedGen UID:
250
Concept ID:
C0002520
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
11.

Protease preparation

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule. [from NCI]

MedGen UID:
45389
Concept ID:
C0030946
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
12.

Enzyme activation

Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. [from MeSH]

MedGen UID:
41819
Concept ID:
C0014429
Molecular Function
13.

Pancreatic intracellular protease activation

MedGen UID:
534827
Concept ID:
C0232798
Molecular Function
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