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Mitochondrial inheritance

MedGen UID:
165802
Concept ID:
C0887941
Genetic Function
Synonyms: Inheritance, Mitochondrial; Mitochondrial Inheritance
 
HPO: HP:0001427
Orphanet: ORPHA409933

Definition

A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy). [from HPO]

Recent systematic reviews

Gold M, Rapin I
Int J Pediatr Otorhinolaryngol 1994 Aug;30(2):91-104. PMID: 8063504

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