Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 25

1.

Propionic acid

MedGen UID:
20448
Concept ID:
C0072186
Organic Chemical; Pharmacologic Substance
2.

Glycine

A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells. [from NCI]

MedGen UID:
6636
Concept ID:
C0017890
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
3.

Anesthetics

A drug or other substance that causes a loss of feeling or awareness. Local anesthetics cause a loss of feeling in one small area of the body. Regional anesthetics cause a loss of feeling in a part of the body, such as an arm or leg. General anesthetics cause a loss of feeling and a complete loss of awareness that feels like a very deep sleep. [from NCI]

MedGen UID:
1535
Concept ID:
C0002932
Pharmacologic Substance
4.

Aminobutyric Acid

MedGen UID:
113108
Concept ID:
C0220780
Amino Acid, Peptide, or Protein; Biologically Active Substance; Pharmacologic Substance
5.

Mental Depression

Depression is a serious medical illness that involves the brain. It's more than just a feeling of being "down in the dumps" or "blue" for a few days. If you are one of the more than 20 million people in the United States who have depression, the feelings do not go away. They persist and interfere with your everyday life. Symptoms can include . -Sadness. -Loss of interest or pleasure in activities you used to enjoy. -Change in weight. -Difficulty sleeping or oversleeping. -Energy loss. -Feelings of worthlessness. -Thoughts of death or suicide. Depression is a disorder of the brain. There are a variety of causes, including genetic, environmental, psychological, and biochemical factors. Depression usually starts between the ages of 15 and 30, and is much more common in women. Women can also get postpartum depression after the birth of a baby. Some people get seasonal affective disorder in the winter. Depression is one part of bipolar disorder. There are effective treatments for depression, including antidepressants and talk therapy. Most people do best by using both. . NIH: National Institute of Mental Health.  [from MedlinePlus]

MedGen UID:
8325
Concept ID:
C0011570
Mental or Behavioral Dysfunction
6.

Depression

MedGen UID:
881016
Concept ID:
CN236657
Disease or Syndrome
7.

Pressure

MedGen UID:
632176
Concept ID:
C0460139
Finding
8.

Central nervous system depression

MedGen UID:
508773
Concept ID:
C0151559
Disease or Syndrome; Finding
9.

Disorder of organic acid metabolism

An inherited disorder that affects the metabolism of any acidic compound containing carbon in a covalent linkage. [from NCI]

MedGen UID:
468982
Concept ID:
C1263739
Disease or Syndrome
10.

Methylmalonic acidemia

Isolated methylmalonic acidemia/aciduria, the topic of this GeneReview, is caused by complete or partial deficiency of the enzyme methylmalonyl-CoA mutase (mut(0) enzymatic subtype or mut(–) enzymatic subtype, respectively), a defect in the transport or synthesis of its cofactor, adenosyl-cobalamin (cblA, cblB, or cblD-MMA), or deficiency of the enzyme methylmalonyl-CoA epimerase. Onset of the manifestations of isolated methylmalonic acidemia/aciduria ranges from the neonatal period to adulthood. All phenotypes are characterized by periods of relative health and intermittent metabolic decompensation, usually associated with intercurrent infections and stress. In the neonatal period the disease can present with lethargy, vomiting, hypotonia, hypothermia, respiratory distress, severe ketoacidosis, hyperammonemia, neutropenia, and thrombocytopenia and can result in death within the first four weeks of life. In the infantile/non-B12-responsive phenotype, infants are normal at birth, but develop lethargy, vomiting, dehydration, failure to thrive, hepatomegaly, hypotonia, and encephalopathy within a few weeks to months of age. An intermediate B12-responsive phenotype can occasionally be observed in neonates, but is usually observed in the first months or years of life; affected children exhibit anorexia, failure to thrive, hypotonia, and developmental delay, and sometimes have protein aversion and/or vomiting and lethargy after protein intake. Atypical and "benign"/adult methylmalonic acidemia phenotypes are associated with increased, albeit mild, urinary excretion of methylmalonate. Major secondary complications of methylmalonic acidemia include: intellectual impairment (variable); tubulointerstitial nephritis with progressive renal failure; “metabolic stroke” (acute and chronic basal ganglia injury) causing a disabling movement disorder with choreoathetosis, dystonia, and para/quadriparesis; pancreatitis; growth failure; functional immune impairment; and optic nerve atrophy. [from GeneReviews]

MedGen UID:
120654
Concept ID:
C0268583
Disease or Syndrome
11.

Isovaleryl-CoA dehydrogenase deficiency

Isovaleric acidemia is an inborn error of leucine metabolism caused by a deficiency of isovaleryl-CoA dehydrogenase. It can present with severe neonatal ketoacidosis leading to death, but in milder cases recurrent episodes of ketoacidosis of varying degree occur later in infancy and childhood (summary by Vockley et al., 1991). [from OMIM]

MedGen UID:
82822
Concept ID:
C0268575
Disease or Syndrome
12.

Lateral

Situated at or extending to the side. [from NCI]

MedGen UID:
64373
Concept ID:
C0205093
Spatial Concept
13.

Central

Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure. [from HPO]

MedGen UID:
59958
Concept ID:
C0205099
Spatial Concept
14.

Depression

A condition characterized by pervasive dysphoric mood, loss of interests, and inability to experience pleasure. [from HPO]

MedGen UID:
4229
Concept ID:
C0011581
Mental or Behavioral Dysfunction
15.

Phosphatidylcholine

Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a choline moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and choline and 2 moles of fatty acids. [from MeSH]

MedGen UID:
368756
Concept ID:
C1959616
Biologically Active Substance; Lipid; Organic Chemical; Pharmacologic Substance
16.

Anesthetics, Inhalation

Gases or volatile liquids that vary in the rate at which they induce anesthesia; potency; the degree of circulation, respiratory, or neuromuscular depression they produce; and analgesic effects. Inhalation anesthetics have advantages over intravenous agents in that the depth of anesthesia can be changed rapidly by altering the inhaled concentration. Because of their rapid elimination, any postoperative respiratory depression is of relatively short duration. (From AMA Drug Evaluations Annual, 1994, p173) [from MeSH]

MedGen UID:
66176
Concept ID:
C0242903
Pharmacologic Substance
17.

Isoflurane

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects. [from MeSH]

MedGen UID:
5908
Concept ID:
C0022180
Organic Chemical; Pharmacologic Substance
18.

General anesthetic drugs

Agents that induce various degrees of analgesia; depression of consciousness, circulation, and respiration; relaxation of skeletal muscle; reduction of reflex activity; and amnesia. There are two types of general anesthetics, inhalation and intravenous. With either type, the arterial concentration of drug required to induce anesthesia varies with the condition of the patient, the desired depth of anesthesia, and the concomitant use of other drugs. (From AMA Drug Evaluations Annual, 1994, p.173) [from MeSH]

MedGen UID:
4861
Concept ID:
C0017302
Pharmacologic Substance
19.

Ethers

organic compound having an oxygen atom bonded to two carbon atoms, general formula R-O-R'. [from CRISP]

MedGen UID:
4564
Concept ID:
C0014996
Organic Chemical; Pharmacologic Substance
20.

Electrolyte

substance that while in solution or its pure state will conduct an electric current by means of the movement of ions; in physiology, usually refers to compounds such as sodium, potassium, magnesium and calcium which dissociate fluids into ions that conduct electric currents and that constitute the major force in controlling fluid balance within the body. [from CRISP]

MedGen UID:
3997
Concept ID:
C0013832
Inorganic Chemical; Pharmacologic Substance
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center