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Items: 15

1.

Psychoactive substance dependence

Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug. [from NCI]

MedGen UID:
307144
Concept ID:
C1510472
Mental or Behavioral Dysfunction
2.

Cocaine dependence

A psychologically and socially impaired state, with or without physiological changes, that develops as a result of using cocaine and which leads to compulsive behaviors to acquire the substance. [from NCI]

MedGen UID:
154705
Concept ID:
C0600427
Mental or Behavioral Dysfunction
3.

Alcohol dependence

A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) [from MeSH]

MedGen UID:
1801
Concept ID:
C0001973
Mental or Behavioral Dysfunction
4.

Much

A subjective response indicating that something is or was a large amount. [from NCI]

MedGen UID:
923949
Concept ID:
C4281574
Finding
5.

Alcoholism

MedGen UID:
910816
Concept ID:
CN241664
Finding
6.

Indifference to pain, congenital, autosomal recessive

Hereditary sensory and autonomic neuropathy type II (HSAN2) is characterized by progressively reduced sensation to pain, temperature, and touch. Onset can be at birth and is often before puberty. The sensory deficit is predominantly distal with the lower limbs more severely affected than the upper limbs. Over time sensory function becomes severely reduced. Unnoticed injuries and neuropathic skin promote ulcerations and infections that result in spontaneous amputation of digits or the need for surgical amputation. Osteomyelitis is common. Painless fractures can complicate the disease. Autonomic disturbances are variable and can include hyperhidrosis, tonic pupils, and urinary incontinence in those with more advanced disease. [from GTR]

MedGen UID:
344563
Concept ID:
C1855739
Disease or Syndrome
7.

Paranoia

A persecutory delusion of supposed hostility of others. [from HPO]

MedGen UID:
306130
Concept ID:
C1456784
Mental or Behavioral Dysfunction
8.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
9.

Endoglycosidases

MedGen UID:
760845
Concept ID:
C3537242
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
10.

Diagnosis, Psychiatric

MedGen UID:
138165
Concept ID:
C0376338
Mental or Behavioral Dysfunction
11.

Substance-Related Disorder

A category of psychiatric disorders which include disorders related to the taking of a drug of abuse (including alcohol, prescribed medications and recreational drugs). [from NCI]

MedGen UID:
66746
Concept ID:
C0236969
Mental or Behavioral Dysfunction
12.

Cocaine-induced organic mental disorder

Disorders related or resulting from use of cocaine. [from MeSH]

MedGen UID:
66741
Concept ID:
C0236736
Mental or Behavioral Dysfunction
13.

Mental disorder

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [from NCI]

MedGen UID:
14047
Concept ID:
C0004936
Mental or Behavioral Dysfunction
14.

Glycosidase

covering the sugar hydrolases. [from CRISP]

MedGen UID:
5349
Concept ID:
C0017976
Amino Acid, Peptide, or Protein; Enzyme; Pharmacologic Substance
15.

Cocaine-Related Disorders

MedGen UID:
910419
Concept ID:
CN240612
Disease or Syndrome
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