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Items: 5

1.

Carcinogenesis

The process by which normal cells are transformed into cancer cells. [from NCI_NCI-GLOSS]

MedGen UID:
154544
Concept ID:
C0596263
Neoplastic Process
2.

Atorvastatin

a kind of cholesterol lowering drug [from CHV]

MedGen UID:
84701
Concept ID:
C0286651
Organic Chemical; Pharmacologic Substance
3.

Lovastatin

A drug used to lower the amount of cholesterol in the blood. It is also being studied in the prevention and treatment of some types of cancer. Lovastatin is a type of HMG-CoA reductase inhibitor (statin). [from NCI_NCI-GLOSS]

MedGen UID:
44198
Concept ID:
C0024027
Organic Chemical; Pharmacologic Substance
4.

Lack of Efficacy

The lack of expected or desired effect related to a therapy. [from NCI]

MedGen UID:
68623
Concept ID:
C0235828
Finding
5.

bexarotene

A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42117&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42117&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1635" NCI Thesaurus) [from PDQ]

MedGen UID:
206403
Concept ID:
C0765273
Organic Chemical; Pharmacologic Substance
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