Format
Items per page

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 36

1.

Independent

MedGen UID:
721426
Concept ID:
C1299583
Finding
2.

metaplastic cell transformation

The conversion of a cell from a normal phenotype, which undergoes a limited number of mitotic divisions, into an aberrant phenotype that is immortal and divides indefinitely. Transformed cells no longer retain cell-cycle checkpoints and may ultimately become malignant cancer cells via additional genetic mutations, or damaging environmental events. [from NCI]

MedGen UID:
266929
Concept ID:
C1510411
Pathologic Function
3.

Carcinogenesis

The process by which normal cells are transformed into cancer cells. [from NCI_NCI-GLOSS]

MedGen UID:
154544
Concept ID:
C0596263
Neoplastic Process
4.

Adenocarcinoma

Cancer that begins in cells that line certain internal organs and that have gland-like (secretory) properties. [from NCI_NCI-GLOSS]

MedGen UID:
122
Concept ID:
C0001418
Neoplastic Process
5.

Hedgehog Signaling Pathway

The Hedgehog (Hh) family of secreted signaling proteins plays a crucial role in development of diverse animal phyla, from Drosophila to humans, regulating morphogenesis of a variety of tissues and organs. Hh signaling is also involved in control of stem cell proliferation in adult tissues and aberrant activation of the Hh pathway has been linked to multiple types of human cancer. Members of the Hh family bind to patched (ptc), thus releasing smoothened (smo) to transduce a signal. Transcriptional activation occurs through the GLI family of proteins resulting in activation of target genes. [from NCI_KEGG]

MedGen UID:
452886
Concept ID:
C1155468
Molecular Function
6.

Pancreatic Ductal Adenocarcinoma

An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor. [from NCI]

MedGen UID:
277490
Concept ID:
C1335302
Neoplastic Process
7.

Negative

An absence finding of the specified component / analyte, organism or clinical sign based on the established threshold of the performed test or procedure. [Note: Negative does not necessarily imply the complete absence of the specified item.].  [from HL7]

MedGen UID:
61377
Concept ID:
C0205160
Finding
8.

Signal Transduction Pathways

An elaboration of the known or inferred interactions involved in a signal transduction pathway. [from NCI]

MedGen UID:
39530
Concept ID:
C0086982
Molecular Function
9.

Epithelial Neoplasm

A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas. [from NCI]

MedGen UID:
277963
Concept ID:
C1368683
Neoplastic Process
10.

Ductal Carcinoma

Malignant neoplasms involving the ductal systems of any of a number of organs, such as the MAMMARY GLANDS, the PANCREAS, the PROSTATE, or the LACRIMAL GLAND. [from MeSH]

MedGen UID:
225902
Concept ID:
C1176475
Neoplastic Process
11.

Carcinoma, Pancreatic Ductal

Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS. [from MeSH]

MedGen UID:
165776
Concept ID:
C0887833
Neoplastic Process
12.

Neoplasms, Ductal, Lobular, and Medullary

Neoplasms, usually carcinoma, located within the center of an organ or within small lobes, and in the case of the breast, intraductally. The emphasis of the name is on the location of the neoplastic tissue rather than on its histological type. Most cancers of this type are located in the breast. [from MeSH]

MedGen UID:
104937
Concept ID:
C0206768
Neoplastic Process
13.

Carcinomatosis

Carcinoma that has spread diffusely to an anatomic site or throughout the body. [from NCI]

MedGen UID:
104704
Concept ID:
C0205699
Neoplastic Process
14.

Cribriform Carcinoma

A carcinoma characterized by the presence of a cribriform architectural pattern. Representative examples include the intraductal cribriform breast carcinoma and invasive cribriform breast carcinoma. [from NCI]

MedGen UID:
104694
Concept ID:
C0205643
Neoplastic Process
15.

Tubular Adenocarcinoma

An infiltrating adenocarcinoma in which the malignant cells form tubular structures. Representative examples include the tubular breast carcinoma and the gastric tubular adenocarcinoma. [from NCI]

MedGen UID:
61428
Concept ID:
C0205645
Neoplastic Process
16.

Oxyphilic Adenocarcinoma

An adenocarcinoma characterized by the presence of large malignant epithelial cells with abundant granular eosinophilic cytoplasm (oncocytes). Representative examples include thyroid gland oncocytic follicular carcinoma, oncocytic breast carcinoma, and salivary gland oncocytic carcinoma. [from NCI]

MedGen UID:
61427
Concept ID:
C0205642
Neoplastic Process
17.

Undifferentiated Carcinoma

A malignant epithelial neoplasm exhibiting poor differentiation (anaplasia). [from NCI_CDISC]

MedGen UID:
60010
Concept ID:
C0205698
Neoplastic Process
18.

Sarcomatoid Carcinoma

A malignant epithelial neoplasm characterized by the presence of spindle cells. [from NCI_CDISC]

MedGen UID:
60009
Concept ID:
C0205697
Neoplastic Process
19.

Carcinoma, anaplastic

MedGen UID:
60008
Concept ID:
C0205696
Neoplastic Process
20.

Pancreatic Neoplasms

A tumor (abnormal growth of tissue) of the pancreas. [from HPO]

MedGen UID:
18279
Concept ID:
C0030297
Neoplastic Process
Format
Items per page

Send to:

Choose Destination

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center