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Gluten intolerance

MedGen UID:
775770
Concept ID:
CN182651
Pathologic Function
 

Definition

A detrimental reaction to the presence of gluten in food, which may include abdominal pain, fatigue, headaches and paresthesia, or celiac disease. [from HPO]

Recent clinical studies

Etiology

Quaglia S, De Leo L, Ziberna F, Vatta S, Villanacci V, Granzotto M, Petix V, Martelossi S, Di Leo G, Torelli L, Not T
Cell Mol Immunol 2014 Nov;11(6):617-20. Epub 2014 Apr 28 doi: 10.1038/cmi.2014.32. PMID: 24769794Free PMC Article
Volta U, Tovoli F, Cicola R, Parisi C, Fabbri A, Piscaglia M, Fiorini E, Caio G
J Clin Gastroenterol 2012 Sep;46(8):680-5. doi: 10.1097/MCG.0b013e3182372541. PMID: 22138844
Sáez LR, Álvarez DF, Martínez IP, Mieres NA, García PN, García Rde F, Menéndez SR, Alegre SV, Goñi JL
Rev Esp Enferm Dig 2011 Jul;103(7):349-54. PMID: 21770680
Llorente-Alonso MJ, Fernández-Acenero MJ, Sebastián M
Can J Gastroenterol 2006 Nov;20(11):719-22. PMID: 17111054Free PMC Article
Humbert P, Pelletier F, Dreno B, Puzenat E, Aubin F
Eur J Dermatol 2006 Jan-Feb;16(1):4-11. PMID: 16436335

Diagnosis

Czaja-Bulsa G
Clin Nutr 2015 Apr;34(2):189-94. Epub 2014 Aug 29 doi: 10.1016/j.clnu.2014.08.012. PMID: 25245857
Quaglia S, De Leo L, Ziberna F, Vatta S, Villanacci V, Granzotto M, Petix V, Martelossi S, Di Leo G, Torelli L, Not T
Cell Mol Immunol 2014 Nov;11(6):617-20. Epub 2014 Apr 28 doi: 10.1038/cmi.2014.32. PMID: 24769794Free PMC Article
Volta U, Tovoli F, Cicola R, Parisi C, Fabbri A, Piscaglia M, Fiorini E, Caio G
J Clin Gastroenterol 2012 Sep;46(8):680-5. doi: 10.1097/MCG.0b013e3182372541. PMID: 22138844
Bizzaro N, Tozzoli R, Villalta D, Fabris M, Tonutti E
Clin Rev Allergy Immunol 2012 Jun;42(3):279-87. doi: 10.1007/s12016-010-8223-1. PMID: 21181303
Not T, Ziberna F, Vatta S, Quaglia S, Martelossi S, Villanacci V, Marzari R, Florian F, Vecchiet M, Sulic AM, Ferrara F, Bradbury A, Sblattero D, Ventura A
Gut 2011 Nov;60(11):1487-93. Epub 2011 Apr 6 doi: 10.1136/gut.2010.232900. PMID: 21471568

Therapy

Czaja-Bulsa G
Clin Nutr 2015 Apr;34(2):189-94. Epub 2014 Aug 29 doi: 10.1016/j.clnu.2014.08.012. PMID: 25245857
Quaglia S, De Leo L, Ziberna F, Vatta S, Villanacci V, Granzotto M, Petix V, Martelossi S, Di Leo G, Torelli L, Not T
Cell Mol Immunol 2014 Nov;11(6):617-20. Epub 2014 Apr 28 doi: 10.1038/cmi.2014.32. PMID: 24769794Free PMC Article
Bernardo D, Peña AS
Eur J Intern Med 2012 Jan;23(1):6-8. Epub 2011 Oct 26 doi: 10.1016/j.ejim.2011.09.016. PMID: 22153523
Ruuskanen A, Luostarinen L, Collin P, Krekelä I, Patrikainen H, Tillonen J, Laurila K, Haimila K, Partanen J, Mäki M, Valve R, Kaukinen K
Dig Liver Dis 2011 Oct;43(10):772-8. Epub 2011 Jun 8 doi: 10.1016/j.dld.2011.04.025. PMID: 21641886
Not T, Ziberna F, Vatta S, Quaglia S, Martelossi S, Villanacci V, Marzari R, Florian F, Vecchiet M, Sulic AM, Ferrara F, Bradbury A, Sblattero D, Ventura A
Gut 2011 Nov;60(11):1487-93. Epub 2011 Apr 6 doi: 10.1136/gut.2010.232900. PMID: 21471568

Prognosis

Quaglia S, De Leo L, Ziberna F, Vatta S, Villanacci V, Granzotto M, Petix V, Martelossi S, Di Leo G, Torelli L, Not T
Cell Mol Immunol 2014 Nov;11(6):617-20. Epub 2014 Apr 28 doi: 10.1038/cmi.2014.32. PMID: 24769794Free PMC Article
Not T, Ziberna F, Vatta S, Quaglia S, Martelossi S, Villanacci V, Marzari R, Florian F, Vecchiet M, Sulic AM, Ferrara F, Bradbury A, Sblattero D, Ventura A
Gut 2011 Nov;60(11):1487-93. Epub 2011 Apr 6 doi: 10.1136/gut.2010.232900. PMID: 21471568
Llorente-Alonso MJ, Fernández-Acenero MJ, Sebastián M
Can J Gastroenterol 2006 Nov;20(11):719-22. PMID: 17111054Free PMC Article
Humbert P, Pelletier F, Dreno B, Puzenat E, Aubin F
Eur J Dermatol 2006 Jan-Feb;16(1):4-11. PMID: 16436335
Bardella MT, Fredella C, Saladino V, Trovato C, Cesana BM, Quatrini M, Prampolini L
Scand J Gastroenterol 2005 Jan;40(1):15-9. PMID: 15841709

Clinical prediction guides

Przybylska-Felus M, Furgala A, Zwolinska-Wcislo M, Mazur M, Widera A, Thor P, Mach T
J Physiol Pharmacol 2014 Dec;65(6):833-41. PMID: 25554987
Not T, Ziberna F, Vatta S, Quaglia S, Martelossi S, Villanacci V, Marzari R, Florian F, Vecchiet M, Sulic AM, Ferrara F, Bradbury A, Sblattero D, Ventura A
Gut 2011 Nov;60(11):1487-93. Epub 2011 Apr 6 doi: 10.1136/gut.2010.232900. PMID: 21471568
di Cagno R, de Angelis M, Alfonsi G, de Vincenzi M, Silano M, Vincentini O, Gobbetti M
J Agric Food Chem 2005 Jun 1;53(11):4393-402. doi: 10.1021/jf048341+. PMID: 15913301
Nowowiejska B, Kaczmarski M, Dabrowska EJ
Rocz Akad Med Bialymst 1995;40(3):580-7. PMID: 8775310
Kaczmarski M, Kurzatkowska B
Rocz Akad Med Bialymst 1988-1989;33-34:167-76. PMID: 3154973

Recent systematic reviews

Molina-Infante J, Santolaria S, Sanders DS, Fernández-Bañares F
Aliment Pharmacol Ther 2015 May;41(9):807-20. Epub 2015 Mar 6 doi: 10.1111/apt.13155. PMID: 25753138
Ludvigsson JF, Leffler DA, Bai JC, Biagi F, Fasano A, Green PH, Hadjivassiliou M, Kaukinen K, Kelly CP, Leonard JN, Lundin KE, Murray JA, Sanders DS, Walker MM, Zingone F, Ciacci C
Gut 2013 Jan;62(1):43-52. Epub 2012 Feb 16 doi: 10.1136/gutjnl-2011-301346. PMID: 22345659Free PMC Article
Newnham ED
J Gastroenterol Hepatol 2011 Apr;26 Suppl 3:132-4. doi: 10.1111/j.1440-1746.2011.06653.x. PMID: 21443726
Fan X, Sellin JH
Aliment Pharmacol Ther 2009 May 15;29(10):1069-77. Epub 2009 Feb 15 doi: 10.1111/j.1365-2036.2009.03970.x. PMID: 19222407

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