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Fibromyalgia

MedGen UID:
42018
Concept ID:
C0016053
Disease or Syndrome
Synonyms: Diffuse Myofascial Pain Syndrome; Fibromyalgia Fibromyositis Syndrome; Fibromyalgia-Fibromyositis Syndrome; Fibromyalgia-Fibromyositis Syndromes; Fibromyalgias; Fibromyositis Fibromyalgia Syndrome; Fibromyositis-Fibromyalgia Syndrome; Fibromyositis-Fibromyalgia Syndromes; Fibrositides; Fibrositis; Muscular Rheumatism; Myofascial Pain Syndrome, Diffuse; Rheumatism, Muscular; Syndrome, Fibromyalgia-Fibromyositis; Syndrome, Fibromyositis-Fibromyalgia; Syndromes, Fibromyalgia-Fibromyositis; Syndromes, Fibromyositis-Fibromyalgia
SNOMED CT: MPDS - Myofacial pain dysfunction syndrome (24693007); Myofacial pain dysfunction syndrome (24693007); Fibromyalgia (203082005); Muscular rheumatism (203102006); Myofascial pain dysfunction syndrome (24693007); MPDS (Myofascial pain dysfunction syndrome) (24693007); Fibromyositis (24693007); Myofascial pain syndrome (24693007); Fibromyalgia (24693007); Diffuse myofascial pain syndrome (24693007); Fibrositis (24693007); Fibrositis (56557000)
 

Definition

Fibromyalgia is a disorder that causes muscle pain and fatigue. People with fibromyalgia have tender points on the body. Tender points are specific places on the neck, shoulders, back, hips, arms, and legs. These points hurt when pressure is put on them. People with fibromyalgia may also have other symptoms, such as. -Trouble sleeping. -Morning stiffness. -Headaches. -Painful menstrual periods. -Tingling or numbness in hands and feet. -Problems with thinking and memory (sometimes called fibro fog). No one knows what causes fibromyalgia. Anyone can get it, but it is most common in middle-aged women. People with rheumatoid arthritis and other autoimmune diseases are particularly likely to develop fibromyalgia. There is no cure for fibromyalgia, but medicine can help you manage your symptoms. Getting enough sleep, exercising, and eating well may also help. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases.  [from MedlinePlus]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFibromyalgia

Recent clinical studies

Etiology

Albertoni Giraldes AL, Salomão R, Leal PD, Brunialti MK, Sakata RK
Int J Rheum Dis 2016 Oct;19(10):946-953. Epub 2016 Jun 16 doi: 10.1111/1756-185X.12904. PMID: 27309886
Tatum WO, Langston ME, Acton EK
Epileptic Disord 2016 Jun 1;18(2):148-54. doi: 10.1684/epd.2016.0823. PMID: 27238051
Costantini R, Affaitati G, Massimini F, Tana C, Innocenti P, Giamberardino MA
PLoS One 2016;11(4):e0153408. Epub 2016 Apr 15 doi: 10.1371/journal.pone.0153408. PMID: 27081848Free PMC Article
Gelonch O, Garolera M, Valls J, Rosselló L, Pifarré J
Compr Psychiatry 2016 Apr;66:113-22. Epub 2016 Jan 20 doi: 10.1016/j.comppsych.2016.01.002. PMID: 26995244
Alparslan GB, Babadağ B, Özkaraman A, Yıldız P, Musmul A, Korkmaz C
Clin Rheumatol 2016 May;35(5):1317-21. Epub 2015 Aug 6 doi: 10.1007/s10067-015-3046-3. PMID: 26245724

Diagnosis

Ruggiero V, Mura M, Cacace E, Era B, Peri M, Sanna G, Fais A
Scand J Clin Lab Invest 2017 Apr;77(2):93-97. Epub 2017 Jan 12 doi: 10.1080/00365513.2016.1269362. PMID: 28079404
Albertoni Giraldes AL, Salomão R, Leal PD, Brunialti MK, Sakata RK
Int J Rheum Dis 2016 Oct;19(10):946-953. Epub 2016 Jun 16 doi: 10.1111/1756-185X.12904. PMID: 27309886
Malin K, Littlejohn GO
Clin Rheumatol 2016 Sep;35(9):2353-7. Epub 2016 May 31 doi: 10.1007/s10067-016-3315-9. PMID: 27245234
Tatum WO, Langston ME, Acton EK
Epileptic Disord 2016 Jun 1;18(2):148-54. doi: 10.1684/epd.2016.0823. PMID: 27238051
Collado A, Torres X, Messina OD, Vidal LF, Clark P, Ríos C, Solé E, Arias A, Perrot S, Salomon PA
Pain Med 2016 May;17(5):931-9. Epub 2015 Dec 26 doi: 10.1093/pm/pnv065. PMID: 26814292

Therapy

Cooper TE, Derry S, Wiffen PJ, Moore RA
Cochrane Database Syst Rev 2017 Jan 3;1:CD012188. doi: 10.1002/14651858.CD012188.pub2. PMID: 28045473
Albertoni Giraldes AL, Salomão R, Leal PD, Brunialti MK, Sakata RK
Int J Rheum Dis 2016 Oct;19(10):946-953. Epub 2016 Jun 16 doi: 10.1111/1756-185X.12904. PMID: 27309886
Costantini R, Affaitati G, Massimini F, Tana C, Innocenti P, Giamberardino MA
PLoS One 2016;11(4):e0153408. Epub 2016 Apr 15 doi: 10.1371/journal.pone.0153408. PMID: 27081848Free PMC Article
Alparslan GB, Babadağ B, Özkaraman A, Yıldız P, Musmul A, Korkmaz C
Clin Rheumatol 2016 May;35(5):1317-21. Epub 2015 Aug 6 doi: 10.1007/s10067-015-3046-3. PMID: 26245724
Vincent A, Whipple MO, Rhudy LM
Pain Med 2016 Mar;17(3):463-468. Epub 2016 Mar 1 doi: 10.1111/pme.12676. PMID: 25586303

Prognosis

Maddali Bongi S, Paoletti G, Calà M, Del Rosso A, El Aoufy K, Mikhaylova S
Complement Ther Clin Pract 2016 Aug;24:109-15. Epub 2016 May 27 doi: 10.1016/j.ctcp.2016.05.010. PMID: 27502810
Tatum WO, Langston ME, Acton EK
Epileptic Disord 2016 Jun 1;18(2):148-54. doi: 10.1684/epd.2016.0823. PMID: 27238051
Casanueva B, Belenguer R, Moreno-Muelas JV, Urtiaga J, Urtiaga B, Hernández JL, Pina T, González-Gay MA
Clin Exp Rheumatol 2016 Mar-Apr;34(2 Suppl 96):S125-8. Epub 2016 Apr 7 PMID: 27055283
Kollmann J, Gollwitzer M, Spada MM, Fernie BA
J Psychosom Res 2016 Apr;83:1-9. Epub 2016 Feb 6 doi: 10.1016/j.jpsychores.2016.02.002. PMID: 27020069
Kashikar-Zuck S, King C, Ting TV, Arnold LM
Curr Rheumatol Rep 2016 Apr;18(4):19. doi: 10.1007/s11926-016-0569-9. PMID: 26984803

Clinical prediction guides

Ruggiero V, Mura M, Cacace E, Era B, Peri M, Sanna G, Fais A
Scand J Clin Lab Invest 2017 Apr;77(2):93-97. Epub 2017 Jan 12 doi: 10.1080/00365513.2016.1269362. PMID: 28079404
Albertoni Giraldes AL, Salomão R, Leal PD, Brunialti MK, Sakata RK
Int J Rheum Dis 2016 Oct;19(10):946-953. Epub 2016 Jun 16 doi: 10.1111/1756-185X.12904. PMID: 27309886
Tatum WO, Langston ME, Acton EK
Epileptic Disord 2016 Jun 1;18(2):148-54. doi: 10.1684/epd.2016.0823. PMID: 27238051
Kollmann J, Gollwitzer M, Spada MM, Fernie BA
J Psychosom Res 2016 Apr;83:1-9. Epub 2016 Feb 6 doi: 10.1016/j.jpsychores.2016.02.002. PMID: 27020069
Collado A, Torres X, Messina OD, Vidal LF, Clark P, Ríos C, Solé E, Arias A, Perrot S, Salomon PA
Pain Med 2016 May;17(5):931-9. Epub 2015 Dec 26 doi: 10.1093/pm/pnv065. PMID: 26814292

Recent systematic reviews

Cooper TE, Derry S, Wiffen PJ, Moore RA
Cochrane Database Syst Rev 2017 Jan 3;1:CD012188. doi: 10.1002/14651858.CD012188.pub2. PMID: 28045473
Walitt B, Klose P, Fitzcharles MA, Phillips T, Häuser W
Cochrane Database Syst Rev 2016 Jul 18;7:CD011694. doi: 10.1002/14651858.CD011694.pub2. PMID: 27428009
Walitt B, Klose P, Üçeyler N, Phillips T, Häuser W
Cochrane Database Syst Rev 2016 Jun 2;(6):CD011804. doi: 10.1002/14651858.CD011804.pub2. PMID: 27251337
Rico-Villademoros F, Slim M, Calandre EP
Expert Rev Neurother 2015 Oct;15(10):1123-50. Epub 2015 Sep 22 doi: 10.1586/14737175.2015.1091726. PMID: 26395929
Jones KD, Mist SD, Casselberry MA, Ali A, Christopher MS
Explore (NY) 2015 Jul-Aug;11(4):304-9. Epub 2015 Apr 28 doi: 10.1016/j.explore.2015.04.006. PMID: 26005199Free PMC Article

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