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Royal jelly

MedGen UID:
75158
Concept ID:
C0073603
Lipid; Organic Chemical; Pharmacologic Substance
Synonyms: royal jelly
SNOMED CT: Royal jelly (722195007)
 

Definition

A honey bee secretion that is used in the nutrition of larvae and to stimulate development of adult queens. It contains B-complex vitamins such as pantothenic acid (vitamin B5) and vitamin B6 (pyridoxine), amino acids, minerals, enzymes, monosaccharides and 10-hydroxy-2-decenoic acid (10-HDA). Royal jelly has been shown to have antibacterial and immunomodulatory activities. [from NCI]

Recent clinical studies

Etiology

Chiu HF, Chen BK, Lu YY, Han YC, Shen YC, Venkatakrishnan K, Golovinskaia O, Wang CK
Pharm Biol 2017 Dec;55(1):497-502. doi: 10.1080/13880209.2016.1253110. PMID: 27937077
Khoshpey B, Djazayeri S, Amiri F, Malek M, Hosseini AF, Hosseini S, Shidfar S, Shidfar F
Can J Diabetes 2016 Aug;40(4):324-8. Epub 2016 Mar 22 doi: 10.1016/j.jcjd.2016.01.003. PMID: 27026221
Taavoni S, Barkhordari F, Goushegir A, Haghani H
Complement Ther Med 2014 Aug;22(4):601-6. Epub 2014 May 13 doi: 10.1016/j.ctim.2014.05.004. PMID: 25146061
Musa M, Nasir NF, Thirumulu KP
Afr J Tradit Complement Altern Med 2014;11(1):148-55. Epub 2013 Nov 2 PMID: 24653569Free PMC Article
Pourmoradian S, Mahdavi R, Mobasseri M, Faramarzi E, Mobasseri M
Chin J Integr Med 2014 May;20(5):347-52. Epub 2014 Mar 7 doi: 10.1007/s11655-014-1804-8. PMID: 24610413

Diagnosis

Chiu HF, Chen BK, Lu YY, Han YC, Shen YC, Venkatakrishnan K, Golovinskaia O, Wang CK
Pharm Biol 2017 Dec;55(1):497-502. doi: 10.1080/13880209.2016.1253110. PMID: 27937077
Moriyama T, Yanagihara M, Yano E, Kimura G, Seishima M, Tani H, Kanno T, Nakamura-Hirota T, Hashimoto K, Tatefuji T, Ogawa T, Kawamura Y
Biosci Biotechnol Biochem 2013;77(4):789-95. Epub 2013 Apr 7 doi: 10.1271/bbb.120924. PMID: 23563566
Blank S, Bantleon FI, McIntyre M, Ollert M, Spillner E
Clin Exp Allergy 2012 Jun;42(6):976-85. doi: 10.1111/j.1365-2222.2012.03966.x. PMID: 22909169
Katayama M, Aoki M, Kawana S
J Dermatol 2008 Apr;35(4):222-4. doi: 10.1111/j.1346-8138.2008.00448.x. PMID: 18419679
Takahama H, Shimazu T
J Dermatol 2006 Jun;33(6):424-6. doi: 10.1111/j.1346-8138.2006.00100.x. PMID: 16700835

Therapy

Chiu HF, Chen BK, Lu YY, Han YC, Shen YC, Venkatakrishnan K, Golovinskaia O, Wang CK
Pharm Biol 2017 Dec;55(1):497-502. doi: 10.1080/13880209.2016.1253110. PMID: 27937077
Khoshpey B, Djazayeri S, Amiri F, Malek M, Hosseini AF, Hosseini S, Shidfar S, Shidfar F
Can J Diabetes 2016 Aug;40(4):324-8. Epub 2016 Mar 22 doi: 10.1016/j.jcjd.2016.01.003. PMID: 27026221
Taavoni S, Barkhordari F, Goushegir A, Haghani H
Complement Ther Med 2014 Aug;22(4):601-6. Epub 2014 May 13 doi: 10.1016/j.ctim.2014.05.004. PMID: 25146061
Erdem O, Güngörmüş Z
Holist Nurs Pract 2014 Jul-Aug;28(4):242-6. doi: 10.1097/HNP.0000000000000033. PMID: 24919094
Pourmoradian S, Mahdavi R, Mobasseri M, Faramarzi E, Mobasseri M
Chin J Integr Med 2014 May;20(5):347-52. Epub 2014 Mar 7 doi: 10.1007/s11655-014-1804-8. PMID: 24610413

Prognosis

Lambrinoudaki I, Augoulea A, Rizos D, Politi M, Tsoltos N, Moros M, Chinou I, Graikou K, Kouskouni E, Kambani S, Panoulis K, Moutsatsou P
Gynecol Endocrinol 2016 Oct;32(10):835-839. Epub 2016 May 26 doi: 10.1080/09513590.2016.1188281. PMID: 27227757
Siavash M, Shokri S, Haghighi S, Shahtalebi MA, Farajzadehgan Z
Int Wound J 2015 Apr;12(2):137-42. Epub 2013 Apr 8 doi: 10.1111/iwj.12063. PMID: 23566071
Ford D
Exp Gerontol 2013 Jul;48(7):614-9. Epub 2012 Jul 28 doi: 10.1016/j.exger.2012.07.010. PMID: 22846460
Orhan F, Sekerel BE, Kocabas CN, Sackesen C, Adalioglu G, Tuncer A
Ann Allergy Asthma Immunol 2003 Jun;90(6):611-5. doi: 10.1016/S1081-1206(10)61864-9. PMID: 12839318
Hamerlinck FF
Exp Dermatol 1999 Jun;8(3):167-76. PMID: 10389633

Clinical prediction guides

Chen D, Xin XX, Qian HC, Yu ZY, Shen LR
J Zhejiang Univ Sci B 2016 Jun;17(6):476-83. doi: 10.1631/jzus.B1500295. PMID: 27256681Free PMC Article
Pajovic B, Radojevic N, Dimitrovski A, Tomovic S, Vukovic M
Aging Male 2016 Sep;19(3):192-196. Epub 2016 Apr 5 doi: 10.3109/13685538.2016.1169400. PMID: 27045321
Feng M, Fang Y, Han B, Xu X, Fan P, Hao Y, Qi Y, Hu H, Huo X, Meng L, Wu B, Li J
J Proteome Res 2015 Dec 4;14(12):5327-40. Epub 2015 Nov 3 doi: 10.1021/acs.jproteome.5b00829. PMID: 26496797
Moriyama T, Ito A, Omote S, Miura Y, Tsumoto H
PLoS One 2015;10(5):e0119169. Epub 2015 May 28 doi: 10.1371/journal.pone.0119169. PMID: 26020775Free PMC Article
Taavoni S, Barkhordari F, Goushegir A, Haghani H
Complement Ther Med 2014 Aug;22(4):601-6. Epub 2014 May 13 doi: 10.1016/j.ctim.2014.05.004. PMID: 25146061

Recent systematic reviews

Maier HM, Ilich JZ, Kim JS, Spicer MT
Skinmed 2013 Jul-Aug;11(4):217-24; quiz 224-5. PMID: 24053007

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