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Items: 4

1.

Dopamine

A monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1 adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output. [from NCI]

MedGen UID:
41644
Concept ID:
C0013030
Biologically Active Substance; Neuroreactive Substance or Biogenic Amine; Organic Chemical; Pharmacologic Substance
2.

Xenazine

MedGen UID:
296033
Concept ID:
C1564335
Organic Chemical; Pharmacologic Substance
3.

Nitoman

MedGen UID:
109230
Concept ID:
C0591867
Organic Chemical; Pharmacologic Substance
4.

Tetrabenazine

A drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high affinity label for the vesicle transport system. [from MeSH]

MedGen UID:
11749
Concept ID:
C0039623
Organic Chemical; Pharmacologic Substance
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