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1.

alpha Tocopherol

A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture. [from MeSH]

MedGen UID:
197434
Concept ID:
C0969677
Organic Chemical; Pharmacologic Substance; Vitamin
2.

Tocopherols

group of lipoid antioxidants composed of a bicyclic benzo-gamma- pyran ring system with one or more long aliphatic side chains; dietary requirement of rodents and other animals (but not humans) for normal reproduction, circulation, and muscle and other functions. [from CRISP]

MedGen UID:
39545
Concept ID:
C0087096
Organic Chemical; Pharmacologic Substance; Vitamin
3.

Process

MedGen UID:
923307
Concept ID:
C1951340
Pharmacologic Substance
4.

Acetate

salts or esters of acetic acid in which the terminal hydrogen atom is replaced by a metal, for instance copper acetate Cu(CH3COO)2, or where substitution is by a radical, for instance ethyl acetate CH3COOC2H5. [from CRISP]

MedGen UID:
452099
Concept ID:
C0000975
Organic Chemical; Pharmacologic Substance
5.

alpha-Tocopherol Acetate

MedGen UID:
372839
Concept ID:
C1999896
Organic Chemical; Pharmacologic Substance; Vitamin
6.

Xenobiotic Metabolism

The chemical reactions and physical changes involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e. g. a xenobiotic chemical, such as a pesticide. (Gene Ontology) [from NCI]

MedGen UID:
216948
Concept ID:
C1154744
Molecular Function
7.

VITAMINS,OTHER

Organic substances belonging to diverse chemical families and present in foods in minute amounts, Vitamins are essential to normal metabolism and biochemical functions, usually as coenzymes. Vitamins can be classified by solubility: lipo-soluble (vitamins A, D, E, K, F) and water-soluble (B- complex). Lack of one or more vitamins in the diet cause metabolic deficiency diseases. (NCI04) [from NCI]

MedGen UID:
203015
Concept ID:
C0973669
Organic Chemical; Pharmacologic Substance; Vitamin
8.

Fish-eye disease

Fish-eye disease, also called partial LCAT deficiency, is a disorder that causes the clear front surface of the eyes (the corneas) to gradually become cloudy. The cloudiness, which generally first appears in adolescence or early adulthood, consists of small grayish dots of cholesterol (opacities) distributed across the corneas. Cholesterol is a waxy, fat-like substance that is produced in the body and obtained from foods that come from animals; it aids in many functions of the body but can become harmful in excessive amounts. As fish-eye disease progresses, the corneal cloudiness worsens and can lead to severely impaired vision. [from GHR]

MedGen UID:
83354
Concept ID:
C0342895
Disease or Syndrome
9.

Abortosan

MedGen UID:
368824
Concept ID:
C1963286
Organic Chemical; Pharmacologic Substance; Vitamin
10.

Dal-E

MedGen UID:
280127
Concept ID:
C1529290
Organic Chemical; Pharmacologic Substance; Vitamin
11.

Molecular Mechanisms of Pharmacological Action

Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY. [from MeSH]

MedGen UID:
226255
Concept ID:
C1258062
Molecular Function
12.

Vita-E

MedGen UID:
154504
Concept ID:
C0592257
Organic Chemical; Pharmacologic Substance; Vitamin
13.

Ephynal

MedGen UID:
108811
Concept ID:
C0591450
Organic Chemical; Pharmacologic Substance; Vitamin
14.

E-ferol

MedGen UID:
49452
Concept ID:
C0115296
Organic Chemical; Pharmacologic Substance; Vitamin
15.

Protective agent

A class of agents used in prophylactic or curative therapy to attenuate the negative side effects of toxins or drugs. Protective agents belong to various chemical classes, acting through various pharmacological mechanisms. They may neutralize exogenous poisons, coat mucosa for protection against physical or chemical damage, offer antioxidant protection against free radicals or ionizing radiation, or induce endogenous detoxifying enzymes. (NCI04) [from NCI]

MedGen UID:
19516
Concept ID:
C0033613
Pharmacologic Substance
16.

Vitamin E

Vitamins are substances that your body needs to grow and develop normally. Vitamin E is an antioxidant. It plays a role in your immune system and metabolic processes. Good sources of vitamin E include. -Vegetable oils. -Margarine. -Nuts and seeds. -Leafy greens. Vitamin E is also added to foods like cereals. Most people get enough vitamin E from the foods they eat. People with certain disorders, such as liver diseases, cystic fibrosis, and Crohn's disease may need extra vitamin E. . Vitamin E supplements may be harmful for people who take blood thinners and other medicines. Check with your health care provider before taking the supplements. NIH: National Institutes of Health Office of Dietary Supplements.  [from MedlinePlus]

MedGen UID:
12116
Concept ID:
C0042874
Organic Chemical; Pharmacologic Substance; Vitamin
17.

Pharmaceutical Preparations

You may need to take medicines every day, or only once in a while. Either way, you want to make sure that the medicines are safe and will help you get better. In the United States, the Food and Drug Administration is in charge of assuring the safety and effectiveness of both prescription and over-the-counter medicines. Even safe drugs can cause unwanted side effects or interactions with food or other medicines you may be taking. They may not be safe during pregnancy. To reduce the risk of reactions and make sure that you get better, it is important for you to take your medicines correctly and be careful when giving medicines to children.  [from MedlinePlus]

MedGen UID:
8496
Concept ID:
C0013227
Pharmacologic Substance
18.

Antioxidants

Antioxidants are man-made or natural substances that may prevent or delay some types of cell damage. Antioxidants are found in many foods, including fruits and vegetables. They are also available as dietary supplements. Examples of antioxidants include. - Beta-carotene . - Lutein . - Lycopene. - Selenium. - Vitamin A. - Vitamin C. - Vitamin E. Vegetables and fruits are rich sources of antioxidants. There is good evidence that eating a diet with lots of vegetables and fruits is healthy and lowers risks of certain diseases. But it isn't clear whether this is because of the antioxidants, something else in the foods, or other factors. High-dose supplements of antioxidants may be linked to health risks in some cases. For example, high doses of beta-carotene may increase the risk of lung cancer in smokers. High doses of vitamin E may increase risks of prostate cancer and one type of stroke. Antioxidant supplements may also interact with some medicines. To minimize risk, tell you of your health care providers about any antioxidants you use. NIH: National Center for Complementary and Integrative Health.  [from MedlinePlus]

MedGen UID:
1608
Concept ID:
C0003402
Pharmacologic Substance
19.

TOCOPHEROL,DL-ALPHA

A naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04) [from NCI]

MedGen UID:
232957
Concept ID:
C1323100
Organic Chemical; Pharmacologic Substance; Vitamin
20.

Vitamine E GNR

MedGen UID:
390130
Concept ID:
C2351020
Pharmacologic Substance; Vitamin
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