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Items: 6

1.

Antigen variation

Change in the surface ANTIGEN of a microorganism. There are two different types. One is a phenomenon, especially associated with INFLUENZA VIRUSES, where they undergo spontaneous variation both as slow antigenic drift and sudden emergence of new strains (antigenic shift). The second type is when certain PARASITES, especially trypanosomes, PLASMODIUM, and BORRELIA, survive the immune response of the host by changing the surface coat (antigen switching). (From Herbert et al., The Dictionary of Immunology, 4th ed) [from MeSH]

MedGen UID:
8127
Concept ID:
C0003319
Molecular Function
2.

Infections

MedGen UID:
678472
Concept ID:
C0851162
Disease or Syndrome
3.

Causative_agents

Definition: A factor, such as a microorganism, chemical substance, or form of radiation, whose presence, excessive presence, or (in deficiency diseases) relative absence is essential, in whole or in part, for the occurrence of a condition. Constraint: The use of this participation is limited to observations.  [from HL7]

MedGen UID:
623004
Concept ID:
C0449411
Finding
4.

Protein Function

The action of enzymes, regulators, chaperones etc. [from NCI]

MedGen UID:
279606
Concept ID:
C1527118
Molecular Function
5.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
6.

Central

Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure. [from HPO]

MedGen UID:
59958
Concept ID:
C0205099
Spatial Concept
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