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Items: 4

1.

Goblet cell carcinoma

Goblet cell carcinoma (GCC) is an aggressive type of endocrine tumor of the appendix (see this term) presenting equally in males and females in the fifth decade of life and manifesting with a palpable mass and abdominal pain or acute appendicitis. Metastasis to the ovaries, peritoneum or right colon has usually already occurred in half of patients at the time of diagnosis. [from ORDO]

MedGen UID:
798516
Concept ID:
CN204232
Disease or Syndrome
2.

Appendix Goblet Cell Carcinoid

An invasive mixed adenoneuroendocrine carcinoma of the appendix characterized by a submucosal growth and the presence of neoplastic signet-ring cells resembling goblet cells of the intestine. [from NCI]

MedGen UID:
60007
Concept ID:
C0205695
Neoplastic Process
3.

Carcinoid tumor

A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. [from NCI]

MedGen UID:
2838
Concept ID:
C0007095
Neoplastic Process
4.

Glandular Differentiation

A microscopic finding indicating the presence of cells with glandular differentiation in a tumor sample. [from NCI]

MedGen UID:
354444
Concept ID:
C1711212
Finding
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