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Items: 2

1.

Esomeprazole

The S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell. [from NCI]

MedGen UID:
215246
Concept ID:
C0937846
Organic Chemical; Pharmacologic Substance
2.

Nexium

Esomeprazole magnesium trade name. [from MeSH]

MedGen UID:
215254
Concept ID:
C0939400
Organic Chemical; Pharmacologic Substance

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