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Premature adrenarche

MedGen UID:
137972
Concept ID:
C0342546
Disease or Syndrome
Synonyms: Premature Adrenarche
SNOMED CT: Premature adrenarche (103021001)
 
HPO: HP:0012412

Definition

Onset of adrenarche at an earlier age than usual. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPremature adrenarche

Conditions with this feature

Patterson pseudoleprechaunism syndrome
MedGen UID:
358350
Concept ID:
C1868546
Disease or Syndrome

Recent clinical studies

Etiology

Çelik N, Alp H, Çamtosun E, Alp E, Çelik S, Berk E
Horm Res Paediatr 2017;87(1):7-14. Epub 2016 Nov 22 doi: 10.1159/000452445. PMID: 27871080
Ghanny BA, Malhotra S, Kumta S, Kazachkova I, Homel P, Jacobson-Dickman E, Motaghedi R
J Pediatr Endocrinol Metab 2016 Mar;29(3):351-6. doi: 10.1515/jpem-2015-0252. PMID: 26641961
Voutilainen R, Jääskeläinen J
J Steroid Biochem Mol Biol 2015 Jan;145:226-36. Epub 2014 Jun 9 doi: 10.1016/j.jsbmb.2014.06.004. PMID: 24923732
Neocleous V, Shammas C, Phedonos AP, Karaoli E, Kyriakou A, Toumba M, Phylactou LA, Skordis N
Georgian Med News 2012 Sep;(210):40-7. PMID: 23045419
Livadas S, Dracopoulou M, Vasileiadi K, Lazaropoulou C, Magiakou MA, Xekouki P, Voutetakis A, Kanaka-Gantenbein C, Papassotiriou I, Stefanadis C, Chrousos GP, Dacou-Voutetakis C
Metabolism 2009 Apr;58(4):576-81. doi: 10.1016/j.metabol.2008.12.002. PMID: 19303981

Diagnosis

Ghanny BA, Malhotra S, Kumta S, Kazachkova I, Homel P, Jacobson-Dickman E, Motaghedi R
J Pediatr Endocrinol Metab 2016 Mar;29(3):351-6. doi: 10.1515/jpem-2015-0252. PMID: 26641961
Utriainen P, Laakso S, Liimatta J, Jääskeläinen J, Voutilainen R
Horm Res Paediatr 2015;83(4):221-31. Epub 2015 Feb 7 doi: 10.1159/000369458. PMID: 25676474
Skordis N, Shammas C, Phedonos AA, Kyriakou A, Toumba M, Neocleous V, Phylactou LA
J Endocrinol Invest 2015 May;38(5):535-9. Epub 2014 Dec 7 doi: 10.1007/s40618-014-0223-1. PMID: 25481255
Voutilainen R, Jääskeläinen J
J Steroid Biochem Mol Biol 2015 Jan;145:226-36. Epub 2014 Jun 9 doi: 10.1016/j.jsbmb.2014.06.004. PMID: 24923732
Gönç EN, Ozön ZA, Alikaşifoğlu A, Engiz O, Bulum B, Kandemir N
Turk J Pediatr 2011 May-Jun;53(3):274-80. PMID: 21980808

Therapy

Çelik N, Alp H, Çamtosun E, Alp E, Çelik S, Berk E
Horm Res Paediatr 2017;87(1):7-14. Epub 2016 Nov 22 doi: 10.1159/000452445. PMID: 27871080
Udhane SS, Dick B, Hu Q, Hartmann RW, Pandey AV
Biochem Biophys Res Commun 2016 Sep 2;477(4):1005-10. Epub 2016 Jul 6 doi: 10.1016/j.bbrc.2016.07.019. PMID: 27395338
Sopher AB, Thornton JC, Silfen ME, Manibo A, Oberfield SE, Wang J, Pierson RN Jr, Levine LS, Horlick M
J Clin Endocrinol Metab 2001 Nov;86(11):5269-72. doi: 10.1210/jcem.86.11.8045. PMID: 11701690Free PMC Article
Oberfield SE, Amer T, Tyson D, Soranno D, David R, Lee E, Levine LS
J Clin Endocrinol Metab 1994 Oct;79(4):1102-4. doi: 10.1210/jcem.79.4.7962281. PMID: 7962281
Toscano V, Balducci R, Adamo MV, Mangiantini A, Cives C, Boscherini B
J Steroid Biochem 1989 Feb;32(2):321-6. PMID: 2537914

Prognosis

Çelik N, Alp H, Çamtosun E, Alp E, Çelik S, Berk E
Horm Res Paediatr 2017;87(1):7-14. Epub 2016 Nov 22 doi: 10.1159/000452445. PMID: 27871080
Ghanny BA, Malhotra S, Kumta S, Kazachkova I, Homel P, Jacobson-Dickman E, Motaghedi R
J Pediatr Endocrinol Metab 2016 Mar;29(3):351-6. doi: 10.1515/jpem-2015-0252. PMID: 26641961
Cebeci AN, Taş A
J Clin Res Pediatr Endocrinol 2015 Mar;7(1):45-8. doi: 10.4274/jcrpe.1525. PMID: 25800475Free PMC Article
Gurnurkar S, Arheart KL, Messiah SE, Mankodi A, Carrillo A
J Pediatr Endocrinol Metab 2014 Jan;27(1-2):69-74. doi: 10.1515/jpem-2013-0199. PMID: 23959660
Gönç EN, Ozön ZA, Alikaşifoğlu A, Engiz O, Bulum B, Kandemir N
Turk J Pediatr 2011 May-Jun;53(3):274-80. PMID: 21980808

Clinical prediction guides

Çelik N, Alp H, Çamtosun E, Alp E, Çelik S, Berk E
Horm Res Paediatr 2017;87(1):7-14. Epub 2016 Nov 22 doi: 10.1159/000452445. PMID: 27871080
Cebeci AN, Taş A
J Clin Res Pediatr Endocrinol 2015 Mar;7(1):45-8. doi: 10.4274/jcrpe.1525. PMID: 25800475Free PMC Article
Skordis N, Shammas C, Phedonos AA, Kyriakou A, Toumba M, Neocleous V, Phylactou LA
J Endocrinol Invest 2015 May;38(5):535-9. Epub 2014 Dec 7 doi: 10.1007/s40618-014-0223-1. PMID: 25481255
Utriainen P, Jääskeläinen J, Voutilainen R
J Clin Endocrinol Metab 2013 Jan;98(1):E87-91. Epub 2012 Nov 15 doi: 10.1210/jc.2012-2783. PMID: 23162102
Gönç EN, Ozön ZA, Alikaşifoğlu A, Engiz O, Bulum B, Kandemir N
Turk J Pediatr 2011 May-Jun;53(3):274-80. PMID: 21980808

Recent systematic reviews

Wakeling EL, Brioude F, Lokulo-Sodipe O, O'Connell SM, Salem J, Bliek J, Canton AP, Chrzanowska KH, Davies JH, Dias RP, Dubern B, Elbracht M, Giabicani E, Grimberg A, Grønskov K, Hokken-Koelega AC, Jorge AA, Kagami M, Linglart A, Maghnie M, Mohnike K, Monk D, Moore GE, Murray PG, Ogata T, Petit IO, Russo S, Said E, Toumba M, Tümer Z, Binder G, Eggermann T, Harbison MD, Temple IK, Mackay DJ, Netchine I
Nat Rev Endocrinol 2017 Feb;13(2):105-124. Epub 2016 Sep 2 doi: 10.1038/nrendo.2016.138. PMID: 27585961

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