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Sleep paralysis

MedGen UID:
96820
Concept ID:
C0456511
Pathologic Function
Synonyms: Paralysis, Sleep; Sleep Paralysis
SNOMED CT: Sleep paralysis (277180005)
 
HPO: HP:0025233

Definition

A common condition characterized by transient partial or total paralysis of skeletal muscles and areflexia that occurs upon awakening from sleep or less often while falling asleep. Stimuli such as touch or sound may terminate the episode, which usually has a duration of seconds to minutes. This condition may occur in normal subjects or be associated with NARCOLEPSY; CATAPLEXY; and hypnagogic HALLUCINATIONS. The pathophysiology of this condition is closely related to the normal hypotonia that occur during REM sleep. (From Adv Neurol 1995;67:245-271) [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSleep paralysis

Recent clinical studies

Etiology

Denis D, French CC, Rowe R, Zavos HM, Nolan PM, Parsons MJ, Gregory AM
J Sleep Res 2015 Aug;24(4):438-46. Epub 2015 Feb 9 doi: 10.1111/jsr.12282. PMID: 25659590Free PMC Article
Jalal B, Simons-Rudolph J, Jalal B, Hinton DE
Transcult Psychiatry 2014 Apr;51(2):158-75. Epub 2013 Oct 1 doi: 10.1177/1363461513503378. PMID: 24084761
Sharpless BA, Barber JP
Sleep Med Rev 2011 Oct;15(5):311-5. Epub 2011 May 14 doi: 10.1016/j.smrv.2011.01.007. PMID: 21571556Free PMC Article
Munezawa T, Kaneita Y, Osaki Y, Kanda H, Ohtsu T, Suzuki H, Minowa M, Suzuki K, Higuchi S, Mori J, Ohida T
Sleep Med 2011 Jan;12(1):56-64. doi: 10.1016/j.sleep.2010.04.015. PMID: 20920888
Abrams MP, Mulligan AD, Carleton RN, Asmundson GJ
J Anxiety Disord 2008 Dec;22(8):1535-41. Epub 2008 Mar 13 doi: 10.1016/j.janxdis.2008.03.007. PMID: 18436428

Diagnosis

Jalal B, Hinton DE
J Nerv Ment Dis 2015 Nov;203(11):871-5. doi: 10.1097/NMD.0000000000000382. PMID: 26488914
Bušková J, Piško J, Dostálová S, Růžička E, Sonka K
Sleep Med 2013 Sep;14(9):919-21. Epub 2013 Jun 6 doi: 10.1016/j.sleep.2013.03.019. PMID: 23746823
Sharpless BA, McCarthy KS, Chambless DL, Milrod BL, Khalsa SR, Barber JP
J Clin Psychol 2010 Dec;66(12):1292-306. Epub 2010 Aug 16 doi: 10.1002/jclp.20724. PMID: 20715166Free PMC Article
Hsieh SW, Lai CL, Liu CK, Lan SH, Hsu CY
Qual Life Res 2010 Nov;19(9):1265-72. Epub 2010 Jun 26 doi: 10.1007/s11136-010-9695-4. PMID: 20577906
Jiménez-Genchi A, Avila-Rodríguez VM, Sánchez-Rojas F, Terrez BE, Nenclares-Portocarrero A
Psychiatry Clin Neurosci 2009 Aug;63(4):546-9. Epub 2009 May 22 doi: 10.1111/j.1440-1819.2009.01984.x. PMID: 19496997

Therapy

Koziorynska EI, Rodriguez AJ
Rev Neurol Dis 2011;8(3-4):e97-106. PMID: 22249574
Nishino S, Okuro M
Expert Opin Emerg Drugs 2010 Mar;15(1):139-58. doi: 10.1517/14728210903559852. PMID: 20166851
Uhde TW, Cortese BM, Vedeniapin A
Curr Psychiatry Rep 2009 Aug;11(4):269-76. PMID: 19635234
Galimberti CA, Ossola M, Colnaghi S, Arbasino C
Epilepsy Behav 2009 Mar;14(3):562-4. Epub 2009 Jan 20 doi: 10.1016/j.yebeh.2008.12.018. PMID: 19162231
Gangdev P
Australas Psychiatry 2004 Mar;12(1):77-80. doi: 10.1046/j.1039-8562.2003.02065.x. PMID: 15715746

Prognosis

Jalal B, Ramachandran VS
Med Hypotheses 2014 Dec;83(6):755-7. Epub 2014 Oct 13 doi: 10.1016/j.mehy.2014.10.002. PMID: 25459150
Cheyne JA, Girard TA
Conscious Cogn 2007 Dec;16(4):959-74. Epub 2007 Mar 6 doi: 10.1016/j.concog.2007.01.002. PMID: 17337212
Girard TA, Cheyne JA
J Sleep Res 2006 Jun;15(2):222-9. doi: 10.1111/j.1365-2869.2006.00512.x. PMID: 16704578
Otto MW, Simon NM, Powers M, Hinton D, Zalta AK, Pollack MH
J Anxiety Disord 2006;20(5):687-93. Epub 2005 Aug 11 doi: 10.1016/j.janxdis.2005.07.002. PMID: 16099138
Gangdev P
Australas Psychiatry 2004 Mar;12(1):77-80. doi: 10.1046/j.1039-8562.2003.02065.x. PMID: 15715746

Clinical prediction guides

Jalal B, Ramachandran VS
Med Hypotheses 2014 Dec;83(6):755-7. Epub 2014 Oct 13 doi: 10.1016/j.mehy.2014.10.002. PMID: 25459150
Jiménez-Genchi A, Avila-Rodríguez VM, Sánchez-Rojas F, Terrez BE, Nenclares-Portocarrero A
Psychiatry Clin Neurosci 2009 Aug;63(4):546-9. Epub 2009 May 22 doi: 10.1111/j.1440-1819.2009.01984.x. PMID: 19496997
Kompanje EJ
J Sleep Res 2008 Dec;17(4):464-7. Epub 2008 Aug 5 doi: 10.1111/j.1365-2869.2008.00672.x. PMID: 18691361
Solomonova E, Nielsen T, Stenstrom P, Simard V, Frantova E, Donderi D
Conscious Cogn 2008 Mar;17(1):49-63. Epub 2007 Jun 15 doi: 10.1016/j.concog.2007.04.007. PMID: 17574867
Cheyne JA, Girard TA
Conscious Cogn 2007 Dec;16(4):959-74. Epub 2007 Mar 6 doi: 10.1016/j.concog.2007.01.002. PMID: 17337212

Recent systematic reviews

Kajeepeta S, Gelaye B, Jackson CL, Williams MA
Sleep Med 2015 Mar;16(3):320-30. Epub 2015 Jan 21 doi: 10.1016/j.sleep.2014.12.013. PMID: 25777485Free PMC Article
Boscolo-Berto R, Viel G, Montagnese S, Raduazzo DI, Ferrara SD, Dauvilliers Y
Sleep Med Rev 2012 Oct;16(5):431-43. Epub 2011 Nov 4 doi: 10.1016/j.smrv.2011.09.001. PMID: 22055895
Steine IM, Harvey AG, Krystal JH, Milde AM, Grønli J, Bjorvatn B, Nordhus IH, Eid J, Pallesen S
Sleep Med Rev 2012 Feb;16(1):15-25. Epub 2011 May 19 doi: 10.1016/j.smrv.2011.01.006. PMID: 21600813
Sharpless BA, Barber JP
Sleep Med Rev 2011 Oct;15(5):311-5. Epub 2011 May 14 doi: 10.1016/j.smrv.2011.01.007. PMID: 21571556Free PMC Article
Mohsenin V
Postgrad Med 2009 May;121(3):99-104. doi: 10.3810/pgm.2009.05.2008. PMID: 19491546

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