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Items: 17

1.

Prostaglandins

group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway; extremely potent mediators of a diverse group of physiological processes. [from CRISP]

MedGen UID:
18692
Concept ID:
C0033554
Hormone; Organic Chemical; Pharmacologic Substance
2.

Mitogens

A soluble substance, usually a protein, that induces mitosis in resting cells, thereby causing cell proliferation. [from NCI]

MedGen UID:
7665
Concept ID:
C0026249
Pharmacologic Substance
3.

Sarcoma

Your soft tissues connect, support, or surround other tissues. Examples include your muscles, tendons, fat, and blood vessels. Soft tissue sarcoma is a cancer of these soft tissues. There are many kinds, based on the type of tissue they started in. They may cause a lump or swelling in the soft tissue. Sometimes they spread and can press on nerves and organs, causing problems such as pain or trouble breathing. No one knows exactly what causes these cancers. They are not common, but you have a higher risk if you have been exposed to certain chemicals, have had radiation therapy, or have certain genetic diseases. Doctors diagnose soft tissue sarcomas with a biopsy. Treatments include surgery to remove the tumor, radiation therapy, chemotherapy, or a combination. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
224714
Concept ID:
C1261473
Neoplastic Process
4.

A 603

MedGen UID:
132768
Concept ID:
C0291778
Organic Chemical; Pharmacologic Substance
5.

Separated from cohabitee

Indicates a person living apart from his/her spouse by legal arrangement. [from NCI]

MedGen UID:
88651
Concept ID:
C0086972
Finding
6.

Rous Sarcoma

A fibrosarcoma, originally observed in a Plymouth Rock hen, now thought to be an expression of infection by certain viruses of the avian leukosis-sarcoma complex in the family [from NCI]

MedGen UID:
39719
Concept ID:
C0086942
Experimental Model of Disease; Neoplastic Process
7.

Vesicle

A small (less than 1 cm) fluid-filled lesion, raised above the plane of surrounding skin [from SNOMEDCT_US]

MedGen UID:
568991
Concept ID:
C0333262
Disease or Syndrome
8.

Sarcoma

A connective tissue neoplasm formed by proliferation of mesodermal cells. Bone and soft tissue sarcomas are the main types of sarcoma. Sarcoma is usually highly malignant. [from HPO]

MedGen UID:
506452
Concept ID:
CN117138
Finding
9.

Peptide Biosynthesis

The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. [CHEBI:16670, GOC:dph, GOC:jl] [from GO]

MedGen UID:
272130
Concept ID:
C1327133
Molecular Function
10.

Carcinogenesis

The process by which normal cells are transformed into cancer cells. [from NCI_NCI-GLOSS]

MedGen UID:
154544
Concept ID:
C0596263
Neoplastic Process
11.

Genetic translation

ribosome mediated process by which polypeptide chains are synthesized, the aminoacid sequence being completely determined by the sequence of bases in a messenger RNA, which in turn is determined by the sequences of bases in the DNA of the gene from which it was transcribed. [from CRISP]

MedGen UID:
108933
Concept ID:
C0597295
Molecular Function
12.

Tetradecanoylphorbol Acetate

A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43661&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43661&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C866" NCI Thesaurus) [from PDQ]

MedGen UID:
21493
Concept ID:
C0039654
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
13.

Neoplastic Processes

The pathological mechanisms and forms taken by tissue during degeneration into a neoplasm and its subsequent activity. [from MeSH]

MedGen UID:
14325
Concept ID:
C0027671
Neoplastic Process
14.

Tumorigenesis

A pathologic process that involves the transformation of normal cells to a neoplastic state and resulting in polyclonal or monoclonal neoplastic cell proliferation. [from NCI]

MedGen UID:
3302
Concept ID:
C0007621
Neoplastic Process
15.

Benign tumor of seminal vesicle

MedGen UID:
577309
Concept ID:
C0346217
Neoplastic Process
16.

Malignant tumor of seminal vesicle

MedGen UID:
577308
Concept ID:
C0346216
Neoplastic Process
17.

Seminal Vesicle Neoplasm

A benign or malignant neoplasm that affects the seminal vesicle. Representative examples include cystadenoma and adenocarcinoma. [from NCI]

MedGen UID:
90967
Concept ID:
C0341767
Neoplastic Process
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