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Items: 1 to 20 of 34

1.

Enkephalin, Ala(2)-MePhe(4)-Gly(5)-

An enkephalin analog that selectively binds to the MU OPIOID RECEPTOR. It is used as a model for drug permeability experiments. [from MeSH]

MedGen UID:
105708
Concept ID:
C0525773
Amino Acid, Peptide, or Protein; Pharmacologic Substance
2.

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. [from MeSH]

MedGen UID:
1510
Concept ID:
C0002772
Organic Chemical; Pharmacologic Substance
3.

Opiate agonist

A class of synthetic chemicals/drugs similar to opiates (opium derivatives) with analgesic properties. Due to binding to opiate receptors, opioids mimic opiate activity on neurons, various cells (i.e. lymphocytes), pain suppression and other neurobehavioral activity. (NCI) [from NCI]

MedGen UID:
66892
Concept ID:
C0242402
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
4.

agonists

Used with chemicals, drugs, and endogenous substances to indicate substances or agents that have affinity for a receptor and intrinsic activity at that receptor. (From Textbook of Pharmacology, 1991, p.16) [from MeSH]

MedGen UID:
116746
Concept ID:
C0243192
Pharmacologic Substance
5.

Morphine

An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent exhibits widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction. (NCI04) [from NCI]

MedGen UID:
6438
Concept ID:
C0026549
Organic Chemical; Pharmacologic Substance
6.

Fentanyl

a kind of narcotic pain relieving drug [from CHV]

MedGen UID:
4680
Concept ID:
C0015846
Organic Chemical; Pharmacologic Substance
7.

Dependence

The psychological or physiological need to take a substance in oder to experience its effects or to avoid the effects of its absence. [from NCI]

MedGen UID:
141006
Concept ID:
C0439857
Mental or Behavioral Dysfunction
8.

Opiate

sedative narcotics containing opium [from CHV]

MedGen UID:
138150
Concept ID:
C0376196
Hazardous or Poisonous Substance; Pharmacologic Substance
9.

Physical addiction

The neuroadaptation of the body to the presence of an opioid, and is characterized by the onset of acute symptoms and signs of withdrawal if the opioid is stopped or an opioid antagonist is administered. [from NCI]

MedGen UID:
124455
Concept ID:
C0278080
Mental or Behavioral Dysfunction
10.

Addictive behavior

A recurrent pattern of behavior that is characeterized by the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the person or to others. The repetitive engagement in these behaviors ultimately interferes with functioning in other domains. [from HPO]

MedGen UID:
88373
Concept ID:
C0085281
Mental or Behavioral Dysfunction
11.

disease transmission

Transmission of disease from one individual to another. [from PSY]

MedGen UID:
66979
Concept ID:
C0242781
Pathologic Function
12.

Morphine sulfate

a kind of narcotic pain relieving drug [from CHV]

MedGen UID:
31477
Concept ID:
C0066814
Organic Chemical; Pharmacologic Substance
13.

Analgesics

Pain relievers are medicines that reduce or relieve headaches, sore muscles, arthritis, or other aches and pains. There are many different pain medicines, and each one has advantages and risks. Some types of pain respond better to certain medicines than others. Each person may also have a slightly different response to a pain reliever. . Over-the-counter (OTC) medicines are good for many types of pain. There are two main types of OTC pain medicines: acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin, naproxen (Aleve), and ibuprofen (Advil, Motrin) are examples of OTC NSAIDs. If OTC medicines don't relieve your pain, your doctor may prescribe something stronger. Many NSAIDs are also available at higher prescription doses. The most powerful pain relievers are narcotics. They are very effective, but they can sometimes have serious side effects. Because of the risks, you must use them only under a doctor's supervision. There are many things you can do to help ease pain. Pain relievers are just one part of a pain treatment plan.  [from MedlinePlus]

MedGen UID:
8049
Concept ID:
C0002771
Hazardous or Poisonous Substance; Organic Chemical; Pharmacologic Substance
14.

Duramorph

MedGen UID:
148649
Concept ID:
C0700787
Organic Chemical; Pharmacologic Substance
15.

Diagnosis, Psychiatric

MedGen UID:
138165
Concept ID:
C0376338
Mental or Behavioral Dysfunction
16.

RX-783006

MedGen UID:
105709
Concept ID:
C0525779
Amino Acid, Peptide, or Protein; Pharmacologic Substance
17.

Sensory System Agents

Drugs that act on neuronal sensory receptors resulting in an increase, decrease, or modification of afferent nerve activity. (From Smith and Reynard, Textbook of Pharmacology, 1991, p367) [from MeSH]

MedGen UID:
67054
Concept ID:
C0243058
Pharmacologic Substance
18.

Peripheral Nervous System Agents

Drugs that act principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. (From Smith and Reynard, Textbook of Pharmacology, 1991, p75) [from MeSH]

MedGen UID:
67048
Concept ID:
C0243049
Pharmacologic Substance
19.

Substance-Related Disorders

Disorders related to substance abuse. [from MeSH]

MedGen UID:
66746
Concept ID:
C0236969
Mental or Behavioral Dysfunction
20.

Opiate Alkaloids

broad family of plant alkaloids with narcotic effects; historically used as sedatives, anesthetics, analgesics, and euphoriants; heroin and morphine are highly addictive, abused drugs. [from CRISP]

MedGen UID:
66385
Concept ID:
C0221793
Organic Chemical; Pharmacologic Substance
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