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Items: 15

1.

Ouabain product

A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE. [from MeSH]

MedGen UID:
18228
Concept ID:
C0029904
Organic Chemical; Pharmacologic Substance
2.

Hypertension

Blood pressure that is abnormally high. [from NCI]

MedGen UID:
6969
Concept ID:
C0020538
Disease or Syndrome
3.

Hypertension

A finding of increased blood pressure; not necessarily hypertensive disorder [from SNOMEDCT_US]

MedGen UID:
635666
Concept ID:
C0497247
Finding
4.

Pressure

MedGen UID:
632176
Concept ID:
C0460139
Finding
5.

Popliteal pterygium syndrome lethal type

Bartsocas-Papas syndrome (lethal popliteal pterygium syndrome) is an autosomal recessive disorder characterized by multiple popliteal pterygia, ankyloblepharon, filiform bands between the jaws, cleft lip and palate, and syndactyly. Early lethality is common, although survival into childhood and beyond has been reported (summary by Mitchell et al., 2012). A less severe form of popliteal pterygium syndrome (119500) is caused by mutation in the IRF6 gene (607199). [from GTR]

MedGen UID:
337894
Concept ID:
C1849718
Disease or Syndrome
6.

Mutant

An altered form of an individual, organism, population, or genetic character that differs from the corresponding wild type due to one or more alterations (mutations). [from NCI]

MedGen UID:
109303
Concept ID:
C0596988
Cell or Molecular Dysfunction
7.

Proximal

Localized close to the central point of the body. [from HPO]

MedGen UID:
64374
Concept ID:
C0205107
Spatial Concept
8.

Disease Attributes

Clinical characteristics of disease or illness. [from MeSH]

MedGen UID:
199876
Concept ID:
C0752357
Disease or Syndrome
9.

Genetic predisposition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

MedGen UID:
137259
Concept ID:
C0314657
Organism Attribute
10.

Vascular disorder

A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma. [from NCI]

MedGen UID:
22621
Concept ID:
C0042373
Disease or Syndrome
11.

Strophanthins

A number of different cardioactive glycosides obtained from Strophanthus species. OUABAIN is from S. gratus and CYMARINE from S. kombe. They are used like the digitalis glycosides. [from MeSH]

MedGen UID:
21355
Concept ID:
C0038472
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
12.

Strophanthin

MedGen UID:
21354
Concept ID:
C0038471
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
13.

Disorder of cardiovascular system

A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [from NCI]

MedGen UID:
2848
Concept ID:
C0007222
Disease or Syndrome
14.

Glycoside

Any compound in which a sugar group is covalently bonded through its anomeric carbon to another group via an O-glycosidic bond or an S-glycosidic bond; glycosides involving the latter are also called thioglycosides. However, substances containing N-glycosidic bonds, where the anomeric carbon is bound to some other group via a nitrogen atom, are called glycosylamines; the term "N-glycoside" is considered a misnomer by IUPAC and is discouraged. Furthermore, the sugar group needs to be bonded to a non-sugar for the molecule to qualify as a glycoside, thus excluding the polysaccharides. The sugar group in glycosides is known as the glycone, which can be a single sugar group (monosaccharide) or several sugar groups (oligosaccharide); the non-sugar group is known as the aglycone or genin. [from NCI]

MedGen UID:
770
Concept ID:
C0007158
Organic Chemical; Pharmacologic Substance
15.

Genetic renal tubular disease

MedGen UID:
798447
Concept ID:
CN200561
Disease or Syndrome
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