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Items: 16

1.

Smallpox Vaccine

smallpox vaccine.  [from HL7]

MedGen UID:
20786
Concept ID:
C0037355
Immunologic Factor; Pharmacologic Substance
2.

Smallpox

Smallpox is a disease caused by the Variola major virus. Some experts say that over the centuries it has killed more people than all other infectious diseases combined. Worldwide immunization stopped the spread of smallpox three decades ago. The last case was reported in 1977. Two research labs still keep small amounts of the virus. Experts fear bioterrorists could use the virus to spread disease. Smallpox spreads very easily from person to person. Symptoms are flu-like. They include. -High fever. -Fatigue. -Headache. -Backache. -A rash with flat red sores. There is no treatment. Fluids and medicines for pain or fever can help control symptoms. Most people recover, but some can die. Those who do recover may have severe scars. The U.S. stopped routine smallpox vaccinations in 1972. Military and other high-risk groups continue to get the vaccine. The U.S. has increased its supply of the vaccine in recent years. The vaccine makes some people sick, so doctors save it for those at highest risk of disease. . NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
20785
Concept ID:
C0037354
Disease or Syndrome
3.

Vaccines

A Type of medicine that creates an immune protection without the recipient experiencing the disease.  [from HL7]

MedGen UID:
52963
Concept ID:
C0042210
Immunologic Factor; Pharmacologic Substance
4.

Vaccinia

The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine. [from MeSH]

MedGen UID:
52964
Concept ID:
C0042214
Disease or Syndrome
5.

Cowpox

A mild, eruptive skin disease of milk cows caused by COWPOX VIRUS, with lesions occurring principally on the udder and teats. Human infection may occur while milking an infected animal. [from MeSH]

MedGen UID:
3261
Concept ID:
C0010232
Disease or Syndrome
6.

Mevalonic aciduria

Mevalonic aciduria, the first recognized defect in the biosynthesis of cholesterol and isoprenoids, is a consequence of a deficiency of mevalonate kinase (ATP:mevalonate 5-phosphotransferase; EC 2.7.1.36). Mevalonic acid accumulates because of failure of conversion to 5-phosphomevalonic acid, which is catalyzed by mevalonate kinase. Mevalonic acid is synthesized from 3-hydroxy-3-methylglutaryl-CoA, a reaction catalyzed by HMG-CoA reductase (142910). Mevalonic aciduria is characterized by dysmorphology, psychomotor retardation, progressive cerebellar ataxia, and recurrent febrile crises, usually manifesting in early infancy, accompanied by hepatosplenomegaly, lymphadenopathy, arthralgia, and skin rash. The febrile crises are similar to those observed in hyperimmunoglobulinemia D and to periodic fever syndrome (HIDS; 260920), which is also caused by mutation in the MVK gene (summary by Prietsch et al., 2003). [from OMIM]

MedGen UID:
368373
Concept ID:
C1959626
Disease or Syndrome
7.

Vaccinated (qualifier)

Treated with a vaccine. [from NCI_NCI-GLOSS]

MedGen UID:
274370
Concept ID:
C1519885
Finding
8.

Viral disease

Viruses are capsules with genetic material inside. They are very tiny, much smaller than bacteria. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox and hemorrhagic fevers. . Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This eventually kills the cells, which can make you sick. Viral infections are hard to treat because viruses live inside your body's cells. They are protected from medicines, which usually move through your bloodstream. Antibiotics do not work for viral infections. There are a few antiviral medicines available. Vaccines can help prevent you from getting many viral diseases. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
9.

DNA Virus Infections

Diseases caused by DNA VIRUSES. [from MeSH]

MedGen UID:
41636
Concept ID:
C0012922
Disease or Syndrome
10.

Viral vaccine

Any vaccine preparation composed of a live, attenuated, inactivated, killed or recombinant virus. Administration of a viral vaccine is to provide prophylaxis against viral disease or used as a vehicle to treat cancers. [from NCI]

MedGen UID:
22655
Concept ID:
C0042742
Immunologic Factor; Pharmacologic Substance
11.

Vaccines, Attenuated

living microorganism, usually attenuated, administered to induce an immune response, containing a pathogen that either causes no or acceptable reactions, gives cross protection, or is the actual pathogen against which protection is wanted. [from CRISP]

MedGen UID:
12037
Concept ID:
C0042211
Immunologic Factor; Pharmacologic Substance
12.

Poxviridae Infections

Virus diseases caused by the POXVIRIDAE. [from MeSH]

MedGen UID:
10885
Concept ID:
C0032870
Disease or Syndrome
13.

Biological Products

Complex pharmaceutical substances, preparations, or matter derived from organisms usually obtained by biological methods or assay. [from MeSH]

MedGen UID:
577
Concept ID:
C0005522
Biologically Active Substance; Pharmacologic Substance
14.

Alastrim

A orthopoxvirus that causes a milder clinical syndrome than smallpox. [from NCI]

MedGen UID:
1393
Concept ID:
C0001906
Disease or Syndrome
15.

Disease due to Orthopoxvirus

MedGen UID:
734973
Concept ID:
C1532229
Disease or Syndrome
16.

Modified smallpox

Smallpox that occurs in an individual who has been vaccinated. [from NCI]

MedGen UID:
20788
Concept ID:
C0037358
Disease or Syndrome
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