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Items: 8

1.

Pregnancy

The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. [from NCI]

MedGen UID:
10895
Concept ID:
C0032961
Organism Function
2.

Growth delay

A deficiency or slowing down of growth pre- and postnatally. [from HPO]

MedGen UID:
765377
Concept ID:
C3552463
Sign or Symptom
3.

Intrauterine growth retardation

An abnormal restriction of fetal growth with fetal weight below the tenth percentile for gestational age. [from HPO]

MedGen UID:
473406
Concept ID:
C1386048
Pathologic Function
4.

Preeclampsia

Pregnancy-induced hypertension in association with significant amounts of protein in the urine. [from HPO]

MedGen UID:
451904
Concept ID:
CN117494
Finding
5.

Growth retardation

A deficiency or slowing down of growth pre- and postnatally. [from HPO]

MedGen UID:
56240
Concept ID:
C0151686
Pathologic Function
6.

Preeclampsia/eclampsia 1

Preeclampsia, which along with chronic hypertension and gestational hypertension comprise the hypertensive disorders of pregnancy, is characterized by new hypertension (blood pressure 140/90 or greater) presenting after 20 weeks' gestation with clinically relevant proteinuria. Preeclampsia is 1 of the top 4 causes of maternal mortality and morbidity worldwide (summary by Payne et al., 2011). Preeclampsia is otherwise known as gestational proteinuric hypertension (Davey and MacGillivray, 1988). A high proportion of patients with preeclampsia have glomerular endotheliosis, the unique histopathologic feature of the condition (Fisher et al., 1981). A distinct form of severe preeclampsia is characterized by hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) (Brown et al., 2000). Genetic Heterogeneity of Preeclampsia/Eclampsia Susceptibility loci for preeclampsia/eclampsia include PEE1 on chromosome 2p13, PEE2 (609402) on chromosome 2p25, and PEE3 (609403) on chromosome 9p13. PEE4 (609404) is caused by mutation in the STOX1 gene (609397) on chromosome 10q22. PEE5 (614595) is caused by mutation in the CORIN gene (605236) on chromosome 4p12. An association with PEE has been found with the EPHX1 gene (132810) on chromosome 1q. [from GTR]

MedGen UID:
18608
Concept ID:
C0032914
Finding; Pathologic Function
7.

Multiparous

MedGen UID:
6459
Concept ID:
C0026751
Finding
8.

Intrauterine growth restriction

Failure of a FETUS to attain expected GROWTH. [from MeSH]

MedGen UID:
4693
Concept ID:
C0015934
Pathologic Function
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