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Items: 17

1.

Inflammation

A localized protective response resulting from injury or destruction of tissues. Inflammation serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. In the acute phase, inflammation is characterized by the signs of pain, heat, redness, swelling, and loss of function. Histologically, inflammation involves a complex series of events, including dilatation of arterioles, capillaries, and venules, with increased permeability and blood flow; exudation of fluids, including plasma proteins; and leukocyte migration into the site of inflammation. [from NCI]

MedGen UID:
7072
Concept ID:
C0021368
Pathologic Function
2.

Agonist

A drug or substance that binds to a receptor inside a cell or on its surface and causes the same action as the substance that normally binds to the receptor. [from NCI_NCI-GLOSS]

MedGen UID:
459858
Concept ID:
C2987634
Pharmacologic Substance
3.

TO-901317

MedGen UID:
240996
Concept ID:
C0965514
Organic Chemical; Pharmacologic Substance
4.

Furriers lung

MedGen UID:
538594
Concept ID:
C0264476
Disease or Syndrome
5.

Coffee-workers lung

MedGen UID:
538589
Concept ID:
C0264468
Disease or Syndrome
6.

Cheese-washers lung

MedGen UID:
507549
Concept ID:
C0007969
Disease or Syndrome
7.

Triggered by

In medicine, a specific event that starts a process or that causes a particular outcome. For example, chemotherapy, painful treatments, or the smells, sounds, and sights that go with them may trigger anxiety and fear in a patient who has cancer. In allergies, exposure to mold, pollen or dust may trigger sneezing, watery eyes, and coughing. [from NCI_NCI-GLOSS]

MedGen UID:
252950
Concept ID:
C1444748
Qualitative Concept
8.

Functional disorder

Deranged function in an individual or an organ that is due to a disease. (MedicineNet.com) [from NCI]

MedGen UID:
124450
Concept ID:
C0277785
Pathologic Function
9.

Van der Woude syndrome

IRF6-related disorders span a spectrum from isolated cleft lip and palate and Van der Woude syndrome (VWS) at the mild end to popliteal pterygium syndrome (PPS) at the more severe end. Individuals with VWS show one or more of the following anomalies: Congenital, usually bilateral, paramedian lower-lip fistulae (pits) or sometimes small mounds with a sinus tract leading from a mucous gland of the lip. Cleft lip (CL). Cleft palate (CP). Note: Cleft lip with or without cleft palate (CL±P) is observed about twice as often as CP only. Submucous cleft palate (SMCP). The PPS phenotype includes the following: CL±P. Fistulae of the lower lip. Webbing of the skin extending from the ischial tuberosities to the heels. In males: bifid scrotum and cryptorchidism. In females: hypoplasia of the labia majora. Syndactyly of fingers and/or toes. Anomalies of the skin around the nails. A characteristic pyramidal fold of skin overlying the nail of the hallux (almost pathognomonic). In some non-classic forms of PPS: filiform synechiae connecting the upper and lower jaws (syngnathia) or the upper and lower eyelids (ankyloblepharon). In both VWS and PPS, growth and intelligence are normal. [from GeneReviews]

MedGen UID:
61233
Concept ID:
C0175697
Disease or Syndrome
10.

Inhibition

MedGen UID:
5809
Concept ID:
C0021469
Molecular Function
11.

Disease due to Gram-negative bacteria

Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method. [from MeSH]

MedGen UID:
88406
Concept ID:
C0085423
Disease or Syndrome
12.

Mediator of inflammation

The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC). [from MeSH]

MedGen UID:
66209
Concept ID:
C0243042
Pharmacologic Substance
13.

Sulfone

Any of substance containing a sulfonyl functional group attached to two carbon atoms with antibiotic activity. Tthe general structural formula is R-S(=O)(=O)-R'. [from NCI]

MedGen UID:
21395
Concept ID:
C0038761
Organic Chemical; Pharmacologic Substance
14.

Bacterial Infections

Bacteria are living things that have only one cell. Under a microscope, they look like balls, rods, or spirals. They are so small that a line of 1,000 could fit across a pencil eraser. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. Bacteria are also used in making healthy foods like yogurt and cheese. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Antibiotics are the usual treatment. When you take antibiotics, follow the directions carefully. Each time you take antibiotics, you increase the chances that bacteria in your body will learn to resist them causing antibiotic resistance. Later, you could get or spread an infection that those antibiotics cannot cure. NIH: National Institute of Allergy and Infectious Diseases.  [from MedlinePlus]

MedGen UID:
14012
Concept ID:
C0004623
Disease or Syndrome
15.

Infection due to Enterobacteriaceae

Infections with bacteria of the family ENTEROBACTERIACEAE. [from MeSH]

MedGen UID:
8642
Concept ID:
C0014347
Disease or Syndrome
16.

Infection caused by Klebsiella

Infections with bacteria of the genus KLEBSIELLA. [from MeSH]

MedGen UID:
7222
Concept ID:
C0022729
Disease or Syndrome
17.

Bacterial Infections and Mycoses

Infections caused by bacteria and fungi, general, specified, or unspecified. [from MeSH]

MedGen UID:
2161
Concept ID:
C0004615
Disease or Syndrome
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