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Items: 10

1.

Interleukin-12

A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS. [from MeSH]

MedGen UID:
50116
Concept ID:
C0123759
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
2.

Psoriasis

MedGen UID:
10997
Concept ID:
C0033860
Disease or Syndrome
3.

Chronic small plaque psoriasis

MedGen UID:
590303
Concept ID:
C0406317
Disease or Syndrome
4.

Moderate

Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
525853
Concept ID:
C0205081
Qualitative Concept
5.

Psoriasis

MedGen UID:
505592
Concept ID:
CN003401
Finding
6.

Human Interleukin 12

MedGen UID:
456182
Concept ID:
C2983955
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
7.

Plaque

MedGen UID:
452424
Concept ID:
C0332461
Finding
8.

Severe

Having a high degree of severity. For quantitative traits, a deviation of between four and five standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
104640
Concept ID:
C0205082
Qualitative Concept
9.

Nasopharyngitis

An inflammatory process that affects the nasopharynx. [from NCI]

MedGen UID:
6527
Concept ID:
C0027441
Disease or Syndrome
10.

Injection site reaction

Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA. [from MeSH]

MedGen UID:
101800
Concept ID:
C0151735
Pathologic Function
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