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Items: 1 to 20 of 33

1.

Infection

The invasion of an organism's body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce. [from NCI]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
2.

Absence

MedGen UID:
739164
Concept ID:
C1689985
Anatomical Abnormality
3.

Heterogeneous

The presence of apparently similar characters for which the genetic evidence indicates that different genes or different genetic mechanisms are involved in different pedigrees. In clinical settings genetic heterogeneity refers to the presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene, a finding common to many human diseases including ALZHEIMER DISEASE; CYSTIC FIBROSIS; LIPOPROTEIN LIPASE DEFICIENCY, FAMILIAL; and POLYCYSTIC KIDNEY DISEASES. (Rieger, et al., Glossary of Genetics: Classical and Molecular, 5th ed; Segen, Dictionary of Modern Medicine, 1992) [from MeSH]

MedGen UID:
67020
Concept ID:
C0242960
Organism Attribute
4.

Hiv

An infection caused by the human immunodeficiency virus. [from NCI]

MedGen UID:
5583
Concept ID:
C0019693
Disease or Syndrome
5.

N 30

MedGen UID:
173771
Concept ID:
C0632490
Organic Chemical; Pharmacologic Substance
6.

Viremia

A laboratory test result indicating the presence of a virus in the blood. [from NCI]

MedGen UID:
12097
Concept ID:
C0042749
Disease or Syndrome
7.

Interferon gamma

Interferon gamma (166 aa, ~19 kDa) is encoded by the human IFNG gene. This protein is involved in antiviral activity, macrophage activation, antiproliferative activity and immunopotentiation. [from NCI]

MedGen UID:
5846
Concept ID:
C0021745
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
8.

progressive

MedGen UID:
851455
Concept ID:
CN232553
Finding
9.

Human immunodeficiency virus

MedGen UID:
842721
Concept ID:
C3854222
Disease or Syndrome
10.

Impaired T cell function

MedGen UID:
395415
Concept ID:
C1860127
Finding
11.

Interferon

Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570) [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
12.

Chronic

Slow, creeping onset, slow progress and long continuance of disease manifestations. [from HPO]

MedGen UID:
104657
Concept ID:
C0205191
Temporal Concept
13.

Examined for

Having been subjected to inspection or evaluation. [from NCI]

MedGen UID:
83047
Concept ID:
C0332128
Finding
14.

Progressive

Advancing in extent or severity. [from NCI]

MedGen UID:
64400
Concept ID:
C0205329
Functional Concept
15.

Vaccine

Preparations containing substances with antigenic properties administered to activate the immune system, thereby inducing an immune response. [from NCI]

MedGen UID:
52963
Concept ID:
C0042210
Immunologic Factor; Pharmacologic Substance
16.

Immunodeficiency

Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral. [from MeSH]

MedGen UID:
7034
Concept ID:
C0021051
Disease or Syndrome
17.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
18.

Ro-236019

MedGen UID:
214655
Concept ID:
C0919268
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
19.

Viral Load

The number of viral particles (usually HIV) in a sample of blood plasma.(On-line Medical Dictionary) [from NCI]

MedGen UID:
84035
Concept ID:
C0376705
Finding
20.

Sepsis

Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. [from MeSH]

MedGen UID:
69314
Concept ID:
C0243026
Disease or Syndrome
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