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Items: 6

1.

Indomethacin

A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes. [from MeSH]

MedGen UID:
5786
Concept ID:
C0021246
Organic Chemical; Pharmacologic Substance
2.

symptomatic

MedGen UID:
880232
Concept ID:
CN235625
Finding
3.

Patent ductus arteriosus

In utero, the ductus arteriosus (DA) serves to divert ventricular output away from the lungs and toward the placenta by connecting the main pulmonary artery to the descending aorta. A patent ductus arteriosus (PDA) in the first 3 days of life is a physiologic shunt in healthy term and preterm newborn infants, and normally is substantially closed within about 24 hours after bith and completely closed after about three weeks. Failure of physiologcal closure is referred to a persistent or patent ductus arteriosus (PDA). Depending on the degree of left-to-right shunting, PDA can have clinical consequences. [from HPO]

MedGen UID:
504886
Concept ID:
CN001496
Finding
4.

Patent ductus arteriosus

A congenital defect characterized by the failure of the ductus arteriosus to close soon after birth. As a consequence, blood from the aorta mixes with blood from the pulmonary artery. If untreated, it may lead to congestive heart failure. [from NCI]

MedGen UID:
4415
Concept ID:
C0013274
Congenital Abnormality
5.

Prostaglandin Antagonists

Compounds that inhibit the action of prostaglandins. [from MeSH]

MedGen UID:
10954
Concept ID:
C0033529
Pharmacologic Substance
6.

Decreased urine output

A decreased rate of urine production. [from HPO]

MedGen UID:
854570
Concept ID:
C3887784
Finding
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