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Items: 12

1.

Painful Bladder Syndrome

MedGen UID:
328384
Concept ID:
C1720830
Disease or Syndrome
2.

Ulcerative cystitis

A condition with recurring discomfort or pain in the URINARY BLADDER and the surrounding pelvic region without an identifiable disease. Severity of pain in interstitial cystitis varies greatly and often is accompanied by increased urination frequency and urgency. [from MeSH]

MedGen UID:
129176
Concept ID:
C0282488
Disease or Syndrome
3.

Urinary bladder inflammation

Inflammation of the urinary bladder. [from HPO]

MedGen UID:
8227
Concept ID:
C0010692
Disease or Syndrome
4.

Pain

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. [from MeSH]

MedGen UID:
45282
Concept ID:
C0030193
Sign or Symptom
5.

Hemoclar

MedGen UID:
154679
Concept ID:
C0600295
Organic Chemical; Pharmacologic Substance
6.

Elmiron

MedGen UID:
154678
Concept ID:
C0600293
Organic Chemical; Pharmacologic Substance
7.

PZ-68

MedGen UID:
149232
Concept ID:
C0740026
Organic Chemical; Pharmacologic Substance
8.

SP-54

MedGen UID:
148116
Concept ID:
C0740027
Organic Chemical; Pharmacologic Substance
9.

HOE-BAY 946

MedGen UID:
146332
Concept ID:
C0684241
Organic Chemical; Pharmacologic Substance
10.

Fibrocid

MedGen UID:
109045
Concept ID:
C0600294
Organic Chemical; Pharmacologic Substance
11.

Pentosan

A sulfated pentosyl polysaccharide with heparin-like properties. [from MeSH]

MedGen UID:
18364
Concept ID:
C0030888
Organic Chemical; Pharmacologic Substance
12.

Resiniferatoxin

A naturally occurring capsaicin analog found in the latex of the cactus Euphorbia resinifera with analgesic activity. Resiniferatoxin (RTX) binds to and activates the transient receptor potential vanilloid 1 (TRPV1), a non-selective cation channel in the plasma membrane of primary afferent sensory neurons. This increases the permeability to cations, and leads to an influx of calcium and sodium ions. This results in membrane depolarization, causing an irritant effect, followed by desensitization of the sensory neurons thereby inhibiting signal conduction in afferent pain pathways and causing analgesia. TRPV1, a member of the transient receptor potential channel (TRP) superfamily, is a heat- and chemo-sensitive calcium/sodium ion channel that is selectively expressed in a subpopulation of pain-sensing primary afferent neurons. [from NCI]

MedGen UID:
35158
Concept ID:
C0073081
Organic Chemical; Pharmacologic Substance
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