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Items: 1 to 20 of 25

1.

enzyme activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [ISBN:0198506732] [from GO]

MedGen UID:
66218
Concept ID:
C0243102
Molecular Function
2.

Moderate

Having a medium degree of severity. For quantitative traits, a deviation of between three and four standard deviations from the appropriate population mean. [from HPO]

MedGen UID:
525853
Concept ID:
C0205081
Qualitative Concept
3.

Antisocial behavior

A deliberate pattern of behavior that demonstrates both willful aggression toward other people and an intentional disregard for the common, current norms of social conduct. [from NCI]

MedGen UID:
452292
Concept ID:
C0233523
Mental or Behavioral Dysfunction
4.

Source

Where something is available or from where it originates. [from NCI]

MedGen UID:
99076
Concept ID:
C0449416
Finding
5.

Specific enzyme deficiency

A finding in which there is a subnormal amount of an enzyme. Enzymes are proteins that are necessary in certain catabolic processes. [from NCI]

MedGen UID:
56197
Concept ID:
C0149676
Disease or Syndrome
6.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Organic Chemical; Pharmacologic Substance
7.

Ethyl alcohol

A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES. [from MeSH]

MedGen UID:
186
Concept ID:
C0001962
Organic Chemical; Pharmacologic Substance
8.

Diagnosis, Psychiatric

MedGen UID:
138165
Concept ID:
C0376338
Mental or Behavioral Dysfunction
9.

Genetic predisposition

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions. [from MeSH]

MedGen UID:
137259
Concept ID:
C0314657
Organism Attribute
10.

Alcohol-induced organic mental disorder

Disorders related to or resulting from abuse or mis-use of alcohol. [from MeSH]

MedGen UID:
68632
Concept ID:
C0236664
Mental or Behavioral Dysfunction
11.

Substance-Related Disorder

A category of psychiatric disorders which include disorders related to the taking of a drug of abuse (including alcohol, prescribed medications and recreational drugs). [from NCI]

MedGen UID:
66746
Concept ID:
C0236969
Mental or Behavioral Dysfunction
12.

Psychotherapeutic agent

A classification of medication that acts on the central nervous system, affecting brain function, level of consciousness, mood, emotions, and behavior. [from NCI]

MedGen UID:
46201
Concept ID:
C0033978
Pharmacologic Substance
13.

Personality disorder

A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work. [from NCI]

MedGen UID:
45827
Concept ID:
C0031212
Mental or Behavioral Dysfunction
14.

Mental disorder

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [from NCI]

MedGen UID:
14047
Concept ID:
C0004936
Mental or Behavioral Dysfunction
15.

Alcohol dependence

A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) [from MeSH]

MedGen UID:
1801
Concept ID:
C0001973
Mental or Behavioral Dysfunction
16.

Antisocial personality disorder

A disorder characterized by a pervasive pattern of disregard for and violation of the rights of others that is manifested in childhood or early adolescence. (adapted from DSM-IV) [from NCI]

MedGen UID:
1611
Concept ID:
C0003431
Mental or Behavioral Dysfunction
17.

Central nervous system agent

A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252) [from MeSH]

MedGen UID:
836
Concept ID:
C0007680
Pharmacologic Substance
18.

Antisocial behavior, susceptibility to

MedGen UID:
892016
Concept ID:
CN237820
Disease or Syndrome
19.

Novel psychoactive substance misuse

A new narcotic or psychotropic drug that is not controlled by the United Nations drug conventions, but which may pose a public health threat comparable to that posed by substances listed in these conventions. [from SNOMEDCT_US]

MedGen UID:
886632
Concept ID:
C4075794
Mental or Behavioral Dysfunction
20.

Both parents misuse drugs

MedGen UID:
750151
Concept ID:
C2585898
Finding
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