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Items: 20

1.

Infection

The invasion of an organism's body tissues by disease-causing agents and their multiplication, as well as the reaction by the host to these organisms and/or toxins that the organisms produce. [from NCI]

MedGen UID:
811352
Concept ID:
C3714514
Pathologic Function
2.

Interferon

Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions. [from MeSH]

MedGen UID:
5847
Concept ID:
C0021747
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
3.

Coronavirus infection

Virus diseases caused by the CORONAVIRUS genus. Some specifics include transmissible enteritis of turkeys (ENTERITIS, TRANSMISSIBLE, OF TURKEYS); FELINE INFECTIOUS PERITONITIS; and transmissible gastroenteritis of swine (GASTROENTERITIS, TRANSMISSIBLE, OF SWINE). [from MeSH]

MedGen UID:
61674
Concept ID:
C0206750
Disease or Syndrome
4.

Accumulation

A state characterized by the gradual increase in entities or substances. [from NCI]

MedGen UID:
883922
Concept ID:
C4055506
Finding
5.

Absence

MedGen UID:
739164
Concept ID:
C1689985
Anatomical Abnormality
6.

Interferon

Human interferons have been classified into 3 groups: alpha, beta, and gamma. Both alpha- and beta-IFNs, previously designated type I, are acid-stable, but they differ immunologically and in regard to some biologic and physiochemical properties. The IFNs produced by virus-stimulated leukocytes (leukocyte IFNs) are predominantly of the alpha type. Those produced by lymphoblastoid cells are about 90% alpha and 10% beta. Induced fibroblasts produce mainly or exclusively the beta type. The alpha- and beta-IFNs differ widely in amino acid sequence. The gamma or immune IFNs, which are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized, are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570) [from NCI]

MedGen UID:
196514
Concept ID:
C0733470
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
7.

Pathogenesis

The pathologic, physiologic, or biochemical mechanism resulting in the development of a disease or morbid process. [from NCI]

MedGen UID:
195936
Concept ID:
C0699748
Pathologic Function
8.

Ability to balance

The maintenance of a stable, upright body position. [from NCI]

MedGen UID:
154340
Concept ID:
C0560184
Finding
9.

Immune

Protected against infectious disease by either specific or non-specific mechanisms.(On-line Medical Dictionary) [from NCI]

MedGen UID:
98553
Concept ID:
C0439662
Finding
10.

Oncolysis

The destruction of tumor cells or a reduction in swelling. [from NCI]

MedGen UID:
90709
Concept ID:
C0333516
Neoplastic Process
11.

Recruitment

MedGen UID:
78772
Concept ID:
C0271510
Disease or Syndrome
12.

Central

Applies to an abnormality that is located close to the median plane or midline of the body or of the referenced structure. [from HPO]

MedGen UID:
59958
Concept ID:
C0205099
Spatial Concept
13.

Nidovirales Infections

Infections with viruses of the order NIDOVIRALES. The concept includes ARTERIVIRUS INFECTIONS and CORONAVIRIDAE INFECTIONS. [from MeSH]

MedGen UID:
197455
Concept ID:
C0969753
Disease or Syndrome
14.

Mediator of inflammation

The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC). [from MeSH]

MedGen UID:
66209
Concept ID:
C0243042
Pharmacologic Substance
15.

Viral disease

A general term for diseases caused by viruses. [from MeSH]

MedGen UID:
53027
Concept ID:
C0042769
Disease or Syndrome
16.

Disease due to Coronaviridae

Virus diseases caused by CORONAVIRIDAE. [from MeSH]

MedGen UID:
40491
Concept ID:
C0010078
Disease or Syndrome
17.

RNA Virus Infections

Diseases caused by RNA VIRUSES. [from MeSH]

MedGen UID:
11250
Concept ID:
C0035690
Disease or Syndrome
18.

Interferon Type I

Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (INTERFERON-ALPHA and INTERFERON-BETA). [from MeSH]

MedGen UID:
9509
Concept ID:
C0021743
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
19.

Interferon gamma

Interferon gamma (166 aa, ~19 kDa) is encoded by the human IFNG gene. This protein is involved in antiviral activity, macrophage activation, antiproliferative activity and immunopotentiation. [from NCI]

MedGen UID:
5846
Concept ID:
C0021745
Amino Acid, Peptide, or Protein; Immunologic Factor; Pharmacologic Substance
20.

Morphological abnormality of the central nervous system

A non-neoplastic or neoplastic disorder which affects the brain and/or spinal cord. [from NCI]

MedGen UID:
3306
Concept ID:
C0007682
Disease or Syndrome
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