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Items: 11

1.

NSC 641066

MedGen UID:
118818
Concept ID:
C0614706
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
2.

perillyl alcohol

A substance that is being studied in the prevention of cancer. It belongs to the family of plant drugs called monoterpenes. [from NCI]

MedGen UID:
64721
Concept ID:
C0207661
Biologically Active Substance; Organic Chemical; Pharmacologic Substance
3.

Malignant Breast Neoplasm

Breast cancer affects one in eight women during their lives. Breast cancer kills more women in the United States than any cancer except lung cancer. No one knows why some women get breast cancer, but there are a number of risk factors. Risks that you cannot change include. -Age - the chance of getting breast cancer rises as a woman gets older . -Genes - there are two genes, BRCA1 and BRCA2, that greatly increase the risk. Women who have family members with breast or ovarian cancer may wish to be tested. . -Personal factors - beginning periods before age 12 or going through menopause after age 55. Other risks include being overweight, using hormone replacement therapy (also called menopausal hormone therapy), taking birth control pills, drinking alcohol, not having children or having your first child after age 35 or having dense breasts. Symptoms of breast cancer may include a lump in the breast, a change in size or shape of the breast or discharge from a nipple. Breast self-exam and mammography can help find breast cancer early when it is most treatable. Treatment may consist of radiation, lumpectomy, mastectomy, chemotherapy and hormone therapy. Men can have breast cancer, too, but the number of cases is small. NIH: National Cancer Institute.  [from MedlinePlus]

MedGen UID:
651
Concept ID:
C0006142
Neoplastic Process
4.

SCLEROSING CHOLANGITIS, NEONATAL

Neonatal sclerosing cholangitis is a rare autosomal recessive form of severe liver disease with onset in infancy. Affected infants have jaundice, cholestasis, acholic stools, and progressive liver dysfunction resulting in fibrosis and cirrhosis; most require liver transplantation in the first few decades of life. Cholangiography shows patent biliary ducts, but there are bile duct irregularities (summary by Girard et al., 2016; Grammatikopoulos et al., 2016). [from OMIM]

MedGen UID:
910848
Concept ID:
CN241830
Disease or Syndrome
5.

breast cancer

MedGen UID:
880206
Concept ID:
CN235590
Finding
6.

Neoplasm of the breast

A tumor (abnormal growth of tissue) of the breast. [from HPO]

MedGen UID:
506444
Concept ID:
CN116912
Finding
7.

Neoplasm of breast

Tumors or cancer of the human BREAST. [from MeSH]

MedGen UID:
264172
Concept ID:
C1458155
Neoplastic Process
8.

Breast carcinoma

The presence of a carcinoma of the breast. [from HPO]

MedGen UID:
146260
Concept ID:
C0678222
Neoplastic Process
9.

Alcohol

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity. [from NCI]

MedGen UID:
1400
Concept ID:
C0001975
Organic Chemical; Pharmacologic Substance
10.

Ethanol

If you are like many Americans, you drink alcohol at least occasionally. For many people, moderate drinking is probably safe. It may even have health benefits, including reducing your risk of certain heart problems. For most women and for most people over 65, moderate drinking is no more than three drinks a day or seven drinks per week. For men under 65, it is no more than four drinks a day or 14 drinks per week. Some people should not drink at all, including alcoholics, children, pregnant women, people taking certain medicines, and people with certain medical conditions. If you have questions about whether it is safe for you to drink, speak with your health care provider. Anything more than moderate drinking can be risky. Heavy drinking can lead to alcoholism and alcohol abuse, as well as injuries, liver disease, heart disease, cancer, and other health problems. It can also cause problems at home, at work, and with friends. NIH: National Institute on Alcohol Abuse and Alcoholism.  [from MedlinePlus]

MedGen UID:
186
Concept ID:
C0001962
Organic Chemical; Pharmacologic Substance
11.

Progressive osseous heteroplasia

Progressive osseous heteroplasia is a rare autosomal dominant disorder characterized by dermal ossification beginning in infancy, followed by increasing and extensive bone formation in deep muscle and fascia (Kaplan et al., 1994). The molecular defect causing POH is the same as that causing PPHP: an inactivating GNAS mutation caused only by paternal inheritance of the mutant allele. However, patients with PPHP have a constellation of physical findings referred to as Albright hereditary osteodystrophy (AHO; see 103580) that is often not seen in patients with POH. Bastepe and Juppner (2005) suggested that POH may be an extreme end of the spectrum of the AHO features seen in PPHP. [from OMIM]

MedGen UID:
137714
Concept ID:
C0334041
Neoplastic Process
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