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Complex partial epilepsy

MedGen UID:
43169
Concept ID:
C0085417
Disease or Syndrome
Synonyms: Complex Partial Epilepsy; Complex Partial Seizure Disorder; Disorder, Complex Partial Seizures; Epilepsy, Complex Partial; Epilepsy, Psychic Equivalent; Epilepsy, Psychomotor; Partial Epilepsy, Complex; Psychic Equivalent Epilepsy; Psychomotor Epilepsy; Seizure Disorder, Complex Partial
SNOMED CT: Complex partial epileptic seizure (407675009); Psychomotor epilepsy (361123003)
 

Definition

A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8) [from MeSH]

Term Hierarchy

Recent clinical studies

Etiology

Gorham R, Persinger MA
Epilepsy Behav 2012 Feb;23(2):152-8. Epub 2011 Dec 27 doi: 10.1016/j.yebeh.2011.11.010. PMID: 22206825
Sloan ME, Simard-Tremblay E, Shevell MI
J Child Neurol 2010 Jan;25(1):43-7. Epub 2009 Jun 3 doi: 10.1177/0883073809336126. PMID: 19494358
Rosenberger LR, Zeck J, Berl MM, Moore EN, Ritzl EK, Shamim S, Weinstein SL, Conry JA, Pearl PL, Sato S, Vezina LG, Theodore WH, Gaillard WD
Neurology 2009 May 26;72(21):1830-6. doi: 10.1212/WNL.0b013e3181a7114b. PMID: 19470965Free PMC Article
Gaillard WD, Berl MM, Moore EN, Ritzl EK, Rosenberger LR, Weinstein SL, Conry JA, Pearl PL, Ritter FF, Sato S, Vezina LG, Vaidya CJ, Wiggs E, Fratalli C, Risse G, Ratner NB, Gioia G, Theodore WH
Neurology 2007 Oct 30;69(18):1761-71. doi: 10.1212/01.wnl.0000289650.48830.1a. PMID: 17967992
Stella F, Maciel JA
Arq Neuropsiquiatr 2004 Dec;62(4):983-7. Epub 2004 Dec 15 doi: /S0004-282X2004000600010. PMID: 15608956

Diagnosis

Gorham R, Persinger MA
Epilepsy Behav 2012 Feb;23(2):152-8. Epub 2011 Dec 27 doi: 10.1016/j.yebeh.2011.11.010. PMID: 22206825
Gurnett CA, Veile R, Zempel J, Blackburn L, Lovett M, Bowcock A
Arch Neurol 2008 Apr;65(4):550-3. doi: 10.1001/archneur.65.4.550. PMID: 18413482
Stella F, Maciel JA
Arq Neuropsiquiatr 2004 Dec;62(4):983-7. Epub 2004 Dec 15 doi: /S0004-282X2004000600010. PMID: 15608956
Akman C, Riviello JJ, Madsen JR, Bergin AM
Epilepsia 2003 Jun;44(6):855-8. PMID: 12790902
Ross J, Kearse LA Jr, Barlow MK, Houghton KJ, Cosgrove GR
Epilepsia 2001 Feb;42(2):220-5. PMID: 11240593

Therapy

Sloan ME, Simard-Tremblay E, Shevell MI
J Child Neurol 2010 Jan;25(1):43-7. Epub 2009 Jun 3 doi: 10.1177/0883073809336126. PMID: 19494358
Akman C, Riviello JJ, Madsen JR, Bergin AM
Epilepsia 2003 Jun;44(6):855-8. PMID: 12790902
Ross J, Kearse LA Jr, Barlow MK, Houghton KJ, Cosgrove GR
Epilepsia 2001 Feb;42(2):220-5. PMID: 11240593
Reiter JM, Andrews DJ
Seizure 2000 Apr;9(3):198-203. doi: 10.1053/seiz.1999.0374. PMID: 10775516
Snitz BE, Roman DD, Beniak TE
J Clin Exp Neuropsychol 1996 Oct;18(5):747-54. doi: 10.1080/01688639608408297. PMID: 8941859

Prognosis

Boes AD, Grafft A, Espe-Pfeifer P, Rowe J, Stein MT
J Dev Behav Pediatr 2012 May;33(4):365-8. doi: 10.1097/DBP.0b013e31825417bb. PMID: 22566031
Sepić-Grahovac D, Grahovac T, Ružić-Baršić A, Ružić K, Dadić-Hero E
Psychiatr Danub 2011 Mar;23(1):111-3. PMID: 21448112
Sloan ME, Simard-Tremblay E, Shevell MI
J Child Neurol 2010 Jan;25(1):43-7. Epub 2009 Jun 3 doi: 10.1177/0883073809336126. PMID: 19494358
Hsieh PF
Kaohsiung J Med Sci 1996 Jul;12(7):437-40. PMID: 8753147
Ebersole JS
Brain Topogr 1991 Winter;4(2):113-23. PMID: 1793685

Clinical prediction guides

Gorham R, Persinger MA
Epilepsy Behav 2012 Feb;23(2):152-8. Epub 2011 Dec 27 doi: 10.1016/j.yebeh.2011.11.010. PMID: 22206825
Diamond A, Kenney C, Jankovic J
Mov Disord 2006 Aug;21(8):1273-5. doi: 10.1002/mds.20949. PMID: 16703589
Yalýn O, Arman F, Erdoğan F, Kula M
Epilepsy Behav 2006 May;8(3):542-6. Epub 2006 Mar 9 doi: 10.1016/j.yebeh.2005.12.015. PMID: 16524783
Stella F, Maciel JA
Arq Neuropsiquiatr 2003 Jun;61(2B):335-8. Epub 2003 Jul 28 PMID: 12894263
Snitz BE, Roman DD, Beniak TE
J Clin Exp Neuropsychol 1996 Oct;18(5):747-54. doi: 10.1080/01688639608408297. PMID: 8941859

Recent systematic reviews

Eisenschenk S
Neurologist 2006 Sep;12(5):249-54. doi: 10.1097/01.nrl.0000215743.02301.17. PMID: 16990737
Gamble C, Williamson PR, Chadwick DW, Marson AG
Neurology 2006 May 9;66(9):1310-7. doi: 10.1212/01.wnl.0000210517.03902.6e. PMID: 16682660
Chen DK, So YT, Fisher RS; Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.
Neurology 2005 Sep 13;65(5):668-75. doi: 10.1212/01.wnl.0000178391.96957.d0. PMID: 16157897
Leppik IE, Biton V, Sander JW, Wieser HG
Epilepsia 2003 Dec;44(12):1585-7. PMID: 14636332
Dasheiff RM, Sandberg T, Thompson J, Arrambide S; E03 and E05 Cooperative Study Group.
J Clin Neurophysiol 2001 Jan;18(1):68-74. PMID: 11290941

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